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• W2072266745 endingPage "97" @default.
• W2072266745 startingPage "86" @default.
• W2072266745 abstract "Biodegradable nanocarriers such as lipid- or polymer-based nanoparticles can be designed to improve the efficacy and reduce the toxic side effects of drugs. Under appropriate conditions, nanoprecipitation of a hydrophobic compound solution in a non-solvent can generate a dispersion of nanoparticles with a narrow distribution of sizes without the use of surfactant (“Ouzo” effect). The aim of this review is to present the main parameters controlling the nucleation and growth of aggregates in a supersaturated solution and the characteristics of the obtained nanoparticles. The importance of the kinetics of mixing of the solution containing the hydrophobic compound and the non-solvent is highlighted. Illustrative examples of polymeric nanoparticles for drug delivery or terpenoid-based nanoprodrugs obtained by nanoprecipitation are reported." @default.
• W2072266745 created "2016-06-24" @default.
• W2072266745 creator A5051874193 @default.
• W2072266745 creator A5078174247 @default.
• W2072266745 creator A5089243342 @default.
• W2072266745 date "2014-05-01" @default.
• W2072266745 modified "2023-10-11" @default.
• W2072266745 title "Nanoprecipitation and the “Ouzo effect”: Application to drug delivery devices" @default.
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• W2072266745 doi "https://doi.org/10.1016/j.addr.2013.12.009" @default.
• W2072266745 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24384372" @default.
• W2072266745 hasPublicationYear "2014" @default.
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