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• W2072267114 abstract "According to previous studies, a low-calorie diet provides health benefits and increases lifespan in mammals, including primates. Yet a long-term investigation in rhesus monkeys finds no effect on longevity. See Letter p.318 Restricting food intake has been shown to extend lifespan and improve health in various species. Here, the results of a 23-year study of caloric restriction in rhesus macaque monkeys are reported. When started at older ages, restricting caloric intake did not increase survival, but improved the metabolic profile of the monkeys. Young monkeys on a calorie-restricted diet showed a trend towards a delay in age-associated disease onset, but they, too, showed no increase in lifespan. Given that lifespan studies in humans are impractical, work with non-human primates is as near as we can get, and these results suggest that the effects of caloric restriction in long-lived animals are far from straightforward." @default.
• W2072267114 created "2016-06-24" @default.
• W2072267114 creator A5036998014 @default.
• W2072267114 date "2012-08-29" @default.
• W2072267114 modified "2023-10-18" @default.
• W2072267114 title "Mixed results for dieting monkeys" @default.
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• W2072267114 doi "https://doi.org/10.1038/nature11484" @default.
• W2072267114 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22932269" @default.
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