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- W2072325340 abstract "Considerable evidence indicates that reactive oxygen species play an etiological role in both cardiotoxicity and the skin necrosis induced by adriamycin (ADM). An increase in glutathione peroxidase activity on addition of selenium to cultured MCR-5 lung fibroblasts was observed; this increase was accompanied by enhanced cellular resistance to ADM toxicity. Moreover, the presence of exogenous antioxidant systems, such as superoxide dismutase, catalase, vitamin E, dimethylsulfoxide, and desferroxamine, an iron chelating agent, resulted in significant protection from ADM-mediated damage." @default.
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- W2072325340 date "1981-03-01" @default.
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- W2072325340 title "Lack of inhibition of glutathione reductase by anthracycline antibiotics" @default.
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- W2072325340 doi "https://doi.org/10.1016/0006-2952(81)90148-9" @default.
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