Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072368237> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2072368237 endingPage "775" @default.
- W2072368237 startingPage "769" @default.
- W2072368237 abstract "Treatment with the fluorinated steroid triamcinolone (TR) induced type IIb fiber atrophy and the contractile profile of a slow muscle in rat diaphragm. In contrast, the nonfluorinated steroid prednisolone (PR) caused myogenic changes without fiber atrophy, and increased fatigability. The aim of the present study was to investigate the extent to which these changes were reversed 2 mo after discontinuation of treatment. Adult rats were randomly assigned to receive saline, PR 1.25 or 5 mg/kg, or TR 0.25, 0.5, or 1 mg/kg, intramuscularly daily during 4 wk. Administration of TR resulted in severe loss of body weight and dose-dependent mortality. During recovery, body weight in the TR groups increased gradually, still remaining reduced compared with the other groups. Two months after discontinuation of treatment, diaphragm weight was increased in proportion to body weight. Twitch characteristics, maximal tetanic force, force-frequency curve, and fatigue resistance of isolated diaphragm bundles were similar in all groups. Histologic examination of the diaphragm revealed no gross abnormalities in the PR and TR groups. Mild but significant type IIb fiber atrophy was still present in the diaphragm and gastrocnemius muscle of all TR-treated animals. In conclusion, recovery of alterations in morphology of respiratory and peripheral skeletal muscles induced by administration of TR is prolonged." @default.
- W2072368237 created "2016-06-24" @default.
- W2072368237 creator A5021531229 @default.
- W2072368237 creator A5045128518 @default.
- W2072368237 creator A5046743106 @default.
- W2072368237 creator A5047715110 @default.
- W2072368237 creator A5048619003 @default.
- W2072368237 creator A5076880688 @default.
- W2072368237 date "1996-02-01" @default.
- W2072368237 modified "2023-09-24" @default.
- W2072368237 title "Recovery of corticosteroid-induced changes in contractile properties and morphology of rat diaphragm." @default.
- W2072368237 cites W1567088072 @default.
- W2072368237 cites W1895239221 @default.
- W2072368237 cites W1969556684 @default.
- W2072368237 cites W2027542629 @default.
- W2072368237 cites W2031626872 @default.
- W2072368237 cites W2033115071 @default.
- W2072368237 cites W2067405219 @default.
- W2072368237 cites W2109965174 @default.
- W2072368237 cites W2114963007 @default.
- W2072368237 cites W2119465622 @default.
- W2072368237 cites W2129496928 @default.
- W2072368237 cites W2130069261 @default.
- W2072368237 cites W2133457657 @default.
- W2072368237 cites W2166216165 @default.
- W2072368237 cites W2202461518 @default.
- W2072368237 cites W2225560707 @default.
- W2072368237 cites W2281944571 @default.
- W2072368237 cites W2313629305 @default.
- W2072368237 cites W2337950398 @default.
- W2072368237 doi "https://doi.org/10.1164/ajrccm.153.2.8564131" @default.
- W2072368237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8564131" @default.
- W2072368237 hasPublicationYear "1996" @default.
- W2072368237 type Work @default.
- W2072368237 sameAs 2072368237 @default.
- W2072368237 citedByCount "8" @default.
- W2072368237 countsByYear W20723682372014 @default.
- W2072368237 countsByYear W20723682372018 @default.
- W2072368237 crossrefType "journal-article" @default.
- W2072368237 hasAuthorship W2072368237A5021531229 @default.
- W2072368237 hasAuthorship W2072368237A5045128518 @default.
- W2072368237 hasAuthorship W2072368237A5046743106 @default.
- W2072368237 hasAuthorship W2072368237A5047715110 @default.
- W2072368237 hasAuthorship W2072368237A5048619003 @default.
- W2072368237 hasAuthorship W2072368237A5076880688 @default.
- W2072368237 hasBestOaLocation W20723682372 @default.
- W2072368237 hasConcept C105702510 @default.
- W2072368237 hasConcept C121332964 @default.
- W2072368237 hasConcept C126322002 @default.
- W2072368237 hasConcept C134018914 @default.
- W2072368237 hasConcept C157138929 @default.
- W2072368237 hasConcept C164292776 @default.
- W2072368237 hasConcept C24890656 @default.
- W2072368237 hasConcept C2776715498 @default.
- W2072368237 hasConcept C2776804153 @default.
- W2072368237 hasConcept C2777397205 @default.
- W2072368237 hasConcept C2778715236 @default.
- W2072368237 hasConcept C2781172350 @default.
- W2072368237 hasConcept C71924100 @default.
- W2072368237 hasConceptScore W2072368237C105702510 @default.
- W2072368237 hasConceptScore W2072368237C121332964 @default.
- W2072368237 hasConceptScore W2072368237C126322002 @default.
- W2072368237 hasConceptScore W2072368237C134018914 @default.
- W2072368237 hasConceptScore W2072368237C157138929 @default.
- W2072368237 hasConceptScore W2072368237C164292776 @default.
- W2072368237 hasConceptScore W2072368237C24890656 @default.
- W2072368237 hasConceptScore W2072368237C2776715498 @default.
- W2072368237 hasConceptScore W2072368237C2776804153 @default.
- W2072368237 hasConceptScore W2072368237C2777397205 @default.
- W2072368237 hasConceptScore W2072368237C2778715236 @default.
- W2072368237 hasConceptScore W2072368237C2781172350 @default.
- W2072368237 hasConceptScore W2072368237C71924100 @default.
- W2072368237 hasIssue "2" @default.
- W2072368237 hasLocation W20723682371 @default.
- W2072368237 hasLocation W20723682372 @default.
- W2072368237 hasLocation W20723682373 @default.
- W2072368237 hasOpenAccess W2072368237 @default.
- W2072368237 hasPrimaryLocation W20723682371 @default.
- W2072368237 hasRelatedWork W1966919723 @default.
- W2072368237 hasRelatedWork W1983012135 @default.
- W2072368237 hasRelatedWork W2009877402 @default.
- W2072368237 hasRelatedWork W2014432291 @default.
- W2072368237 hasRelatedWork W2054119993 @default.
- W2072368237 hasRelatedWork W2056503472 @default.
- W2072368237 hasRelatedWork W2071934027 @default.
- W2072368237 hasRelatedWork W2114858141 @default.
- W2072368237 hasRelatedWork W2134223583 @default.
- W2072368237 hasRelatedWork W2341096078 @default.
- W2072368237 hasVolume "153" @default.
- W2072368237 isParatext "false" @default.
- W2072368237 isRetracted "false" @default.
- W2072368237 magId "2072368237" @default.
- W2072368237 workType "article" @default.