FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072368797> ?p ?o ?g. }

• W2072368797 endingPage "261" @default.
• W2072368797 startingPage "261" @default.
• W2072368797 abstract "<h3>Objective</h3>To analyze the characteristics and outcomes following enucleation and pancreatic resections of insulinomas.<h3>Design</h3>Retrospective cohort study; prospective database.<h3>Settings</h3>Academic, tertiary, and referral centers.<h3>Patients</h3>Consecutive patients with insulinomas (symptoms of hyperinsulinism and positive fasting glucose test) who underwent surgical treatment between January 1990 and December 2009.<h3>Main Outcome Measures</h3>Operative morbidity, tumor recurrence, and survival after treatment.<h3>Results</h3>A total of 198 patients (58.5% women; median age, 48 years) were identified. There were 175 (88%) neuroendocrine tumors grade G1 and 23 (12%) neuroendocrine tumors grade G2. Malignant insulinomas defined by lymph node/liver metastases were found in 7 patients (3.5%). Multiple insulinomas were found in 8% of patients, and 5.5% of patients had multiple endocrine neoplasia type 1. Surgical procedures included 106 enucleations (54%) and 92 pancreatic resections (46%). Mortality was nil. Rate of clinically significant pancreatic fistula was 18%. Enucleations had a higher reoperation rate compared with pancreatic resections (8.5% vs 1%; P = .02). Multiple endocrine neoplasia type 1 was significantly associated with younger age at onset (P < .005) and higher rates of malignancies and multiple lesions. Median follow-up was 65 months. Six patients (3%; 5 patients had neuroendocrine tumors grade G2) developed tumor recurrence. Four patients (2%) died of disease. New exocrine (1.5%) and endocrine (4%) insufficiencies were associated only with pancreatic resections.<h3>Conclusions</h3>Outcomes following surgical resection of insulinomas are satisfactory, with no mortality and good functional results. Recurrence is uncommon (3%), and it is more likely associated with neuroendocrine tumors grade G2. Insulinomas in multiple endocrine neoplasia type 1 are at higher risk for being malignant and multifocal, requiring pancreatic resections." @default.
• W2072368797 created "2016-06-24" @default.
• W2072368797 creator A5022335076 @default.
• W2072368797 creator A5033134171 @default.
• W2072368797 creator A5049501797 @default.
• W2072368797 creator A5052291326 @default.
• W2072368797 creator A5054395574 @default.
• W2072368797 creator A5057380925 @default.
• W2072368797 creator A5061725328 @default.
• W2072368797 creator A5063976959 @default.
• W2072368797 creator A5072356061 @default.
• W2072368797 date "2012-03-01" @default.
• W2072368797 modified "2023-10-14" @default.
• W2072368797 title "Surgical Management of Insulinomas" @default.
• W2072368797 cites W1521620129 @default.
• W2072368797 cites W1565087940 @default.
• W2072368797 cites W1578083272 @default.
• W2072368797 cites W1893972519 @default.
• W2072368797 cites W1963847126 @default.
• W2072368797 cites W1966414268 @default.
• W2072368797 cites W1972712771 @default.
• W2072368797 cites W1994893031 @default.
• W2072368797 cites W1997428090 @default.
• W2072368797 cites W1999362464 @default.
• W2072368797 cites W1999848832 @default.
• W2072368797 cites W2002501916 @default.
• W2072368797 cites W2006933963 @default.
• W2072368797 cites W2013851031 @default.
• W2072368797 cites W2013889051 @default.
• W2072368797 cites W2025658180 @default.
• W2072368797 cites W2043486742 @default.
• W2072368797 cites W2058319525 @default.
• W2072368797 cites W2059424770 @default.
• W2072368797 cites W2063178653 @default.
• W2072368797 cites W2078961475 @default.
• W2072368797 cites W2084793761 @default.
• W2072368797 cites W2088408403 @default.
• W2072368797 cites W2090438424 @default.
• W2072368797 cites W2090711301 @default.
• W2072368797 cites W2097855568 @default.
• W2072368797 cites W2109423737 @default.
• W2072368797 cites W2117853299 @default.
• W2072368797 cites W2118149592 @default.
• W2072368797 cites W2118539673 @default.
• W2072368797 cites W2119253566 @default.
• W2072368797 cites W2121443988 @default.
• W2072368797 cites W2130712112 @default.
• W2072368797 cites W2146718153 @default.
• W2072368797 cites W2147127033 @default.
• W2072368797 cites W2148918885 @default.
• W2072368797 cites W2150671437 @default.
• W2072368797 cites W2151455626 @default.
• W2072368797 cites W2160305261 @default.
• W2072368797 cites W2208765355 @default.
• W2072368797 cites W2408403975 @default.
• W2072368797 cites W2500149700 @default.
• W2072368797 cites W2590949024 @default.
• W2072368797 doi "https://doi.org/10.1001/archsurg.2011.1843" @default.
• W2072368797 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22430908" @default.
• W2072368797 hasPublicationYear "2012" @default.
• W2072368797 type Work @default.
• W2072368797 sameAs 2072368797 @default.
• W2072368797 citedByCount "124" @default.
• W2072368797 countsByYear W20723687972012 @default.
• W2072368797 countsByYear W20723687972013 @default.
• W2072368797 countsByYear W20723687972014 @default.
• W2072368797 countsByYear W20723687972015 @default.
• W2072368797 countsByYear W20723687972016 @default.
• W2072368797 countsByYear W20723687972017 @default.
• W2072368797 countsByYear W20723687972018 @default.
• W2072368797 countsByYear W20723687972019 @default.
• W2072368797 countsByYear W20723687972020 @default.
• W2072368797 countsByYear W20723687972021 @default.
• W2072368797 countsByYear W20723687972022 @default.
• W2072368797 countsByYear W20723687972023 @default.
• W2072368797 crossrefType "journal-article" @default.
• W2072368797 hasAuthorship W2072368797A5022335076 @default.
• W2072368797 hasAuthorship W2072368797A5033134171 @default.
• W2072368797 hasAuthorship W2072368797A5049501797 @default.
• W2072368797 hasAuthorship W2072368797A5052291326 @default.
• W2072368797 hasAuthorship W2072368797A5054395574 @default.
• W2072368797 hasAuthorship W2072368797A5057380925 @default.
• W2072368797 hasAuthorship W2072368797A5061725328 @default.
• W2072368797 hasAuthorship W2072368797A5063976959 @default.
• W2072368797 hasAuthorship W2072368797A5072356061 @default.
• W2072368797 hasConcept C104317684 @default.
• W2072368797 hasConcept C126322002 @default.
• W2072368797 hasConcept C141071460 @default.
• W2072368797 hasConcept C167135981 @default.
• W2072368797 hasConcept C185592680 @default.
• W2072368797 hasConcept C188261085 @default.
• W2072368797 hasConcept C2778764654 @default.
• W2072368797 hasConcept C2779066768 @default.
• W2072368797 hasConcept C2780053029 @default.
• W2072368797 hasConcept C2780103800 @default.
• W2072368797 hasConcept C2780911694 @default.
• W2072368797 hasConcept C46699223 @default.
• W2072368797 hasConcept C55493867 @default.

• next