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• W2072401838 abstract "You have accessJournal of UrologyUrodynamics/Incontinence/Female Urology: Urodynamic Testing1 Apr 20101623 CLINICAL AND DEMOGRAPHIC VARIABLES ASSOCIATED WITH STATIC URETHRAL PRESSURE PROFILEMETRY IN PATIENTS UNDERGOING MID URETHRAL SLING SURGERY Toby Chai, Liyuan Huang, Kim Kenton, Holly Richter, Stephen Kraus, Jan Baker, and Heather Litman Toby ChaiToby Chai Baltimore, MD More articles by this author , Liyuan HuangLiyuan Huang Watertown, MA More articles by this author , Kim KentonKim Kenton Maywood, IL More articles by this author , Holly RichterHolly Richter Birmingham, AL More articles by this author , Stephen KrausStephen Kraus San Antonio, TX More articles by this author , Jan BakerJan Baker Salt Lake City, UT More articles by this author , and Heather LitmanHeather Litman Watertown, MA More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2010.02.1403AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES To determine whether any baseline clinical and demographic parameters are associated with maximal urethral closure pressure (MUCP) or functional urethral length (FUL) measured on static urethral pressure profilemetry (UPP) in a cohort of women with stress urinary incontinent females undergoing a midurethral sling (MUS). METHODS The Trial of Midurethral Slings (TOMUS) is a randomized trial comparing outcomes of the retropubic versus transobturator midurethral slings. 597 subjects were randomized. Preoperative demographic, clinical and urodynamic variables such as age, ethnicity, parity, smoking history, estrogen use, history of hysterectomy, and prior urinary incontinence (UI) surgery, body mass index (BMI), Qtip delta angle, pad weight test (PW), Urogenital Distress Index (UDI) and MESA scores, POPQ stage, pelvic muscle contraction strength, first and strong desire, maximum cystometric capacity, mean Pdet at Qmax and uroflow parameters were assessed. Multivariable linear regression was performed to assess which variables were associated with MUCP and/or FUL. RESULTS In the multivariate regression analysis older age (p<0.0001), lower BMI (p=0.02), higher PW (p=0.04), no prior UI surgery (p=0.02) and lower Pdet at Qmax (p<0.0001) were statistically significantly associated with lower MUCP. Older age (p=0.002), lower Qtip delta angle (p=0.006), POPQ stage (p=0.002) and strength of pelvic muscle contractions (p=0.03) were significantly associated with lower FUL. CONCLUSIONS Advancing age, lower BMI, and lower voiding pressures were significantly associated with lower MUCP. These findings are identical to what we have published on clinical and demographic variables associated with valsalva leak point pressure (VLPP) in the Stress Incontinence Surgical Treatment Efficacy Trial (SISTEr) suggesting that MUCP appears to have the similar association with these clincodemographic characteristics as VLPP. © 2010 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 183Issue 4SApril 2010Page: e627 Advertisement Copyright & Permissions© 2010 by American Urological Association Education and Research, Inc.MetricsAuthor Information Toby Chai Baltimore, MD More articles by this author Liyuan Huang Watertown, MA More articles by this author Kim Kenton Maywood, IL More articles by this author Holly Richter Birmingham, AL More articles by this author Stephen Kraus San Antonio, TX More articles by this author Jan Baker Salt Lake City, UT More articles by this author Heather Litman Watertown, MA More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ..." @default.
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