FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072448872> ?p ?o ?g. }

• W2072448872 endingPage "1320" @default.
• W2072448872 startingPage "1315" @default.
• W2072448872 abstract "Long-term survival of animal limb allografts with new immunosuppressant combinations and encouraging results of autologous limb replantations led us to believe that clinical application of hand transplantation in human beings was viable.On Sept 23, 1998, we transplanted the right distal forearm and hand of a brain-dead man aged 41 years on to a man aged 48 years who had had traumatic amputation of the distal third of his right forearm. The donor's arm was irrigated with UW organ preservation solution at 4 degrees C, amputated 5 cm above the elbow, and transported in a cool container. We dissected the donor limb and the recipient's arm simultaneously to identify anatomical structures. Appropriate lengths of viable structures were matched. Transplantation involved bone fixation, arterial and venous anastomoses (ischaemic time 12.5 h), nerve sutures, joining of muscles and tendons, and skin closure. Immunosuppression included antithymocyte globulins, tacrolimus, mycophenolic acid, and prednisone. Maintenance therapy included tacrolimus, mycophenolic acid, and prednisone. Follow-up included routine post-transplant laboratory tests, skin biopsies, intensive physiotherapy, and psychological support.The initial postoperative course was uneventful. No surgical complications were seen. Immunosuppression was well tolerated. Mild clinical and histological signs of cutaneous rejection were seen at weeks 8-9 after surgery. These signs disappeared after prednisone dose was increased (from 20 mg/day to 40 mg/day) and topical application of immunosuppressive creams (tacrolimus, clobetasol). Intensive physiotherapy led to satisfactory progress of motor function. Sensory progress (Tinel's sign) was excellent and reached the wrist crease (20 cm) on day 100 for the median and ulnar nerves, and at least 24 cm to the palm by 6 months when deep pressure, but not light touch sensation, could be felt at the mid palm.Hand allotransplantation is technically feasible. Currently available immunosuppression seems to prevent acute rejection. If no further episode of rejection occurs, the functional prognosis of this graft should be similar to if not better than that reported in large series of autoreconstruction." @default.
• W2072448872 created "2016-06-24" @default.
• W2072448872 creator A5017547592 @default.
• W2072448872 creator A5022316074 @default.
• W2072448872 creator A5024484742 @default.
• W2072448872 creator A5026335637 @default.
• W2072448872 creator A5034176889 @default.
• W2072448872 creator A5062283318 @default.
• W2072448872 creator A5074485303 @default.
• W2072448872 creator A5084681966 @default.
• W2072448872 date "1999-04-01" @default.
• W2072448872 modified "2023-10-17" @default.
• W2072448872 title "Human hand allograft: report on first 6 months" @default.
• W2072448872 cites W1967969518 @default.
• W2072448872 cites W1968328661 @default.
• W2072448872 cites W1980537256 @default.
• W2072448872 cites W1989813993 @default.
• W2072448872 cites W1991448965 @default.
• W2072448872 cites W1991775886 @default.
• W2072448872 cites W1992289669 @default.
• W2072448872 cites W2006192663 @default.
• W2072448872 cites W2008742344 @default.
• W2072448872 cites W2009276527 @default.
• W2072448872 cites W2014565026 @default.
• W2072448872 cites W2018347811 @default.
• W2072448872 cites W2058536256 @default.
• W2072448872 cites W2066425181 @default.
• W2072448872 cites W2067713654 @default.
• W2072448872 cites W2074243828 @default.
• W2072448872 cites W2087550872 @default.
• W2072448872 cites W2104278871 @default.
• W2072448872 cites W2112839426 @default.
• W2072448872 cites W2115583355 @default.
• W2072448872 cites W2131598459 @default.
• W2072448872 cites W2158546946 @default.
• W2072448872 cites W2160593316 @default.
• W2072448872 cites W2399576006 @default.
• W2072448872 doi "https://doi.org/10.1016/s0140-6736(99)02062-0" @default.
• W2072448872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10218530" @default.
• W2072448872 hasPublicationYear "1999" @default.
• W2072448872 type Work @default.
• W2072448872 sameAs 2072448872 @default.
• W2072448872 citedByCount "624" @default.
• W2072448872 countsByYear W20724488722012 @default.
• W2072448872 countsByYear W20724488722013 @default.
• W2072448872 countsByYear W20724488722014 @default.
• W2072448872 countsByYear W20724488722015 @default.
• W2072448872 countsByYear W20724488722016 @default.
• W2072448872 countsByYear W20724488722017 @default.
• W2072448872 countsByYear W20724488722018 @default.
• W2072448872 countsByYear W20724488722019 @default.
• W2072448872 countsByYear W20724488722020 @default.
• W2072448872 countsByYear W20724488722021 @default.
• W2072448872 countsByYear W20724488722022 @default.
• W2072448872 countsByYear W20724488722023 @default.
• W2072448872 crossrefType "journal-article" @default.
• W2072448872 hasAuthorship W2072448872A5017547592 @default.
• W2072448872 hasAuthorship W2072448872A5022316074 @default.
• W2072448872 hasAuthorship W2072448872A5024484742 @default.
• W2072448872 hasAuthorship W2072448872A5026335637 @default.
• W2072448872 hasAuthorship W2072448872A5034176889 @default.
• W2072448872 hasAuthorship W2072448872A5062283318 @default.
• W2072448872 hasAuthorship W2072448872A5074485303 @default.
• W2072448872 hasAuthorship W2072448872A5084681966 @default.
• W2072448872 hasConcept C126322002 @default.
• W2072448872 hasConcept C141071460 @default.
• W2072448872 hasConcept C2776204877 @default.
• W2072448872 hasConcept C2777561873 @default.
• W2072448872 hasConcept C2778033501 @default.
• W2072448872 hasConcept C2778720950 @default.
• W2072448872 hasConcept C2780214079 @default.
• W2072448872 hasConcept C2780252810 @default.
• W2072448872 hasConcept C2909675724 @default.
• W2072448872 hasConcept C2911091166 @default.
• W2072448872 hasConcept C71924100 @default.
• W2072448872 hasConceptScore W2072448872C126322002 @default.
• W2072448872 hasConceptScore W2072448872C141071460 @default.
• W2072448872 hasConceptScore W2072448872C2776204877 @default.
• W2072448872 hasConceptScore W2072448872C2777561873 @default.
• W2072448872 hasConceptScore W2072448872C2778033501 @default.
• W2072448872 hasConceptScore W2072448872C2778720950 @default.
• W2072448872 hasConceptScore W2072448872C2780214079 @default.
• W2072448872 hasConceptScore W2072448872C2780252810 @default.
• W2072448872 hasConceptScore W2072448872C2909675724 @default.
• W2072448872 hasConceptScore W2072448872C2911091166 @default.
• W2072448872 hasConceptScore W2072448872C71924100 @default.
• W2072448872 hasIssue "9161" @default.
• W2072448872 hasLocation W20724488721 @default.
• W2072448872 hasLocation W20724488722 @default.
• W2072448872 hasOpenAccess W2072448872 @default.
• W2072448872 hasPrimaryLocation W20724488721 @default.
• W2072448872 hasRelatedWork W1965326757 @default.
• W2072448872 hasRelatedWork W1967827721 @default.
• W2072448872 hasRelatedWork W1992117911 @default.
• W2072448872 hasRelatedWork W2029770560 @default.
• W2072448872 hasRelatedWork W2033426263 @default.
• W2072448872 hasRelatedWork W20959688 @default.
• W2072448872 hasRelatedWork W2167332360 @default.

• next