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- W2072459342 abstract "The Bohlmann–Rahtz pyridine synthesis and the Hantzsch dihydropyridine synthesis can be carried out in a microwave flow reactor or using a conductive heating flow platform for the continuous processing of material. In the Bohlmann–Rahtz reaction, the use of a Brønsted acid catalyst allows Michael addition and cyclodehydration to be carried out in a single step without isolation of intermediates to give the corresponding trisubstituted pyridine as a single regioisomer in good yield. Furthermore, 3-substituted propargyl aldehydes undergo Hantzsch dihydropyridine synthesis in preference to Bohlmann–Rahtz reaction in a very high yielding process that is readily transferred to continuous flow processing." @default.
- W2072459342 created "2016-06-24" @default.
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- W2072459342 date "2013-09-30" @default.
- W2072459342 modified "2023-10-01" @default.
- W2072459342 title "One-step synthesis of pyridines and dihydropyridines in a continuous flow microwave reactor" @default.
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- W2072459342 doi "https://doi.org/10.3762/bjoc.9.232" @default.
- W2072459342 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3817555" @default.
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