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- W2072482595 abstract "A series of potent dipeptide and tripeptide alpha-ketohydroxamic esters was prepared as inhibitors of recombinant human calpain I. Compound 3c, a Cbz-Leu-Phe hydroxamate, displayed the greatest potency against calpain I (IC(50)=6nM), while two compounds, 3l and 3m, both possessing the Cbz-Leu-Leu-Phe sequence, were the most potent (IC(50)=0.2 microM) in a MOLT-4 cell assay." @default.
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- W2072482595 date "2001-10-01" @default.
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- W2072482595 title "Potent peptide α-Ketohydroxamate inhibitors of recombinant human calpain I" @default.
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- W2072482595 doi "https://doi.org/10.1016/s0960-894x(01)00526-1" @default.
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