FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072495215> ?p ?o ?g. }

• W2072495215 endingPage "487" @default.
• W2072495215 startingPage "480" @default.
• W2072495215 abstract "La metilación del ADN se ha revelado como un mecanismo epigenético fundamental en la regulación de la expresión de genes que controlan funciones celulares cruciales en el desarrollo del cáncer. Defectos en la metilación (tanto hipometilación global como hipermetilación de islas CpG) están implicados en la carcinogénesis colorrectal. Algunos nutrientes ejercen un claro efecto en la metilación, lo que sugiere que algunas diferencias en la incidencia de cáncer colorrectal asociadas a la dieta podrían ser debidas al efecto de esta en la metilación. La presencia de los defectos en la metilación tiene claras implicaciones diagnósticas y de pronóstico. Así, se están ya ensayando diversos tests para el cribado del cáncer colorrectal basados en el análisis de genes metilados bien en heces bien en sangre. Por otro lado, la reversibilidad de los procesos de metilación permite el desarrollo de quimioterapias que regulan este proceso a través de su actividad antineoplásica. DNA methylation is a fundamental epigenetic mechanism in regulating the expression of genes controlling crucial cell functions in cancer development. Methylation defects (both global hypomethylation and hypermethylation of CpG islands) are implicated in colorectal carcinogenesis. Some nutrients have a clear effect on methylation, suggesting that some dietary-associated differences in the incidence of colorectal cancer could be due to the effect of diet on methylation. The presence of methylation defects has clear diagnostic and prognostic implications. Thus, several tests are being used for colorectal cancer screening based on methylated gene analysis, whether in feces or blood. In addition, the reversibility of methylation processes allows the development of chemotherapies that regulate this process through their antineoplastic activity." @default.
• W2072495215 created "2016-06-24" @default.
• W2072495215 creator A5047238535 @default.
• W2072495215 creator A5062623001 @default.
• W2072495215 date "2012-08-01" @default.
• W2072495215 modified "2023-09-25" @default.
• W2072495215 title "Defectos de la metilación del ADN en el cáncer colorrectal esporádico y hereditario" @default.
• W2072495215 cites W1507091468 @default.
• W2072495215 cites W1529905521 @default.
• W2072495215 cites W1530652941 @default.
• W2072495215 cites W1578006057 @default.
• W2072495215 cites W1909483570 @default.
• W2072495215 cites W1923908314 @default.
• W2072495215 cites W1965262464 @default.
• W2072495215 cites W1965486483 @default.
• W2072495215 cites W1972254989 @default.
• W2072495215 cites W1975163559 @default.
• W2072495215 cites W1976786479 @default.
• W2072495215 cites W1977501586 @default.
• W2072495215 cites W1983072552 @default.
• W2072495215 cites W1984646383 @default.
• W2072495215 cites W1986149950 @default.
• W2072495215 cites W1998170462 @default.
• W2072495215 cites W2008471043 @default.
• W2072495215 cites W2013521944 @default.
• W2072495215 cites W2014529941 @default.
• W2072495215 cites W2018871664 @default.
• W2072495215 cites W2026645946 @default.
• W2072495215 cites W2027312402 @default.
• W2072495215 cites W2029033394 @default.
• W2072495215 cites W2035462330 @default.
• W2072495215 cites W2054020882 @default.
• W2072495215 cites W2054823635 @default.
• W2072495215 cites W2069096225 @default.
• W2072495215 cites W2096371251 @default.
• W2072495215 cites W2098475463 @default.
• W2072495215 cites W2101170994 @default.
• W2072495215 cites W2103041478 @default.
• W2072495215 cites W2107972234 @default.
• W2072495215 cites W2122555310 @default.
• W2072495215 cites W2123278251 @default.
• W2072495215 cites W2124271295 @default.
• W2072495215 cites W2124855963 @default.
• W2072495215 cites W2127431151 @default.
• W2072495215 cites W2128146359 @default.
• W2072495215 cites W2130444138 @default.
• W2072495215 cites W2131617435 @default.
• W2072495215 cites W2136864841 @default.
• W2072495215 cites W2148521032 @default.
• W2072495215 cites W2152203766 @default.
• W2072495215 cites W2156843318 @default.
• W2072495215 cites W2159899668 @default.
• W2072495215 cites W2161989604 @default.
• W2072495215 cites W2163975490 @default.
• W2072495215 cites W2169768491 @default.
• W2072495215 cites W2170134268 @default.
• W2072495215 doi "https://doi.org/10.1016/j.gastrohep.2012.01.010" @default.
• W2072495215 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22459641" @default.
• W2072495215 hasPublicationYear "2012" @default.
• W2072495215 type Work @default.
• W2072495215 sameAs 2072495215 @default.
• W2072495215 citedByCount "4" @default.
• W2072495215 countsByYear W20724952152013 @default.
• W2072495215 countsByYear W20724952152020 @default.
• W2072495215 crossrefType "journal-article" @default.
• W2072495215 hasAuthorship W2072495215A5047238535 @default.
• W2072495215 hasAuthorship W2072495215A5062623001 @default.
• W2072495215 hasConcept C104317684 @default.
• W2072495215 hasConcept C121608353 @default.
• W2072495215 hasConcept C138885662 @default.
• W2072495215 hasConcept C140173407 @default.
• W2072495215 hasConcept C150194340 @default.
• W2072495215 hasConcept C153911025 @default.
• W2072495215 hasConcept C15708023 @default.
• W2072495215 hasConcept C190727270 @default.
• W2072495215 hasConcept C33288867 @default.
• W2072495215 hasConcept C41091548 @default.
• W2072495215 hasConcept C54355233 @default.
• W2072495215 hasConcept C555283112 @default.
• W2072495215 hasConcept C86803240 @default.
• W2072495215 hasConceptScore W2072495215C104317684 @default.
• W2072495215 hasConceptScore W2072495215C121608353 @default.
• W2072495215 hasConceptScore W2072495215C138885662 @default.
• W2072495215 hasConceptScore W2072495215C140173407 @default.
• W2072495215 hasConceptScore W2072495215C150194340 @default.
• W2072495215 hasConceptScore W2072495215C153911025 @default.
• W2072495215 hasConceptScore W2072495215C15708023 @default.
• W2072495215 hasConceptScore W2072495215C190727270 @default.
• W2072495215 hasConceptScore W2072495215C33288867 @default.
• W2072495215 hasConceptScore W2072495215C41091548 @default.
• W2072495215 hasConceptScore W2072495215C54355233 @default.
• W2072495215 hasConceptScore W2072495215C555283112 @default.
• W2072495215 hasConceptScore W2072495215C86803240 @default.
• W2072495215 hasIssue "7" @default.
• W2072495215 hasLocation W20724952151 @default.
• W2072495215 hasLocation W20724952152 @default.
• W2072495215 hasOpenAccess W2072495215 @default.
• W2072495215 hasPrimaryLocation W20724952151 @default.

• next