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- W2072527944 abstract "[3H]Nipecotic acid was shown to be preferentially accumulated by the same cochlear structures which selectively accumulate [3H]gamma-aminobutyric acid ([3H]-GABA), including the terminals of a subset of olivocochlear neurons. With both amino acids, olivocochlear fibers selectively transported label in a retrograde direction, from cochlea to brainstem. However, only [3H]nipecotic acid produced dense labeling, and labeling of cell bodies in the superior olive, presumably because it is metabolized very slowly. Nipecotic acid appears to provide a selective retrograde tracer, specific to neurons whose terminals exhibit preferential GABA uptake." @default.
- W2072527944 created "2016-06-24" @default.
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- W2072527944 date "1986-12-01" @default.
- W2072527944 modified "2023-10-18" @default.
- W2072527944 title "Nipecotic acid: preferential accumulation in the cochlea by GABA uptake systems and selective retrograde transport to brainstem" @default.
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- W2072527944 doi "https://doi.org/10.1016/0006-8993(86)91536-2" @default.
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