Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072534308> ?p ?o ?g. }
- W2072534308 endingPage "10371" @default.
- W2072534308 startingPage "10366" @default.
- W2072534308 abstract "This study has examined the atomic-level dynamics of the protein in the capsid of filamentous phage Pf1. This capsid consists of approximately 7,300 small subunits of only 46 aa in a helical array around a highly extended, circular single-stranded DNA molecule of 7,349 nt. Measurements were made of site-specific, solid-state NMR order parameters, S, the values which are dimensionless quantities between 0 (mobile) and 1 (static) that characterize the amplitudes of molecular bond angular motions that are faster than microseconds. It was found that the protein subunit backbone is very static, and of particular interest, it appears to be static at residues glycine 15 and glutamine 16 where it had been previously thought to be mobile. In contrast to the backbone, several side chains display large-amplitude angular motions. Side chains on the virion exterior that interact with solvent are highly mobile, but surprisingly, the side chains of residues arginine 44 and lysine 45 near the DNA deep in the interior of the virion are also highly mobile. The large-amplitude dynamic motion of these positively charged side chains in their interactions with the DNA were not previously expected. The results reveal a highly dynamic aspect of a DNA-protein interface within a virus." @default.
- W2072534308 created "2016-06-24" @default.
- W2072534308 creator A5018859062 @default.
- W2072534308 creator A5047667506 @default.
- W2072534308 creator A5085362874 @default.
- W2072534308 date "2008-07-29" @default.
- W2072534308 modified "2023-10-06" @default.
- W2072534308 title "Conformational dynamics of an intact virus: Order parameters for the coat protein of Pf1 bacteriophage" @default.
- W2072534308 cites W1545017391 @default.
- W2072534308 cites W1559204971 @default.
- W2072534308 cites W1763144417 @default.
- W2072534308 cites W1971013220 @default.
- W2072534308 cites W1972921099 @default.
- W2072534308 cites W1974997405 @default.
- W2072534308 cites W1976034641 @default.
- W2072534308 cites W1983316882 @default.
- W2072534308 cites W1983410419 @default.
- W2072534308 cites W1983710854 @default.
- W2072534308 cites W1989490595 @default.
- W2072534308 cites W1991431023 @default.
- W2072534308 cites W1992588170 @default.
- W2072534308 cites W1995728078 @default.
- W2072534308 cites W2000975541 @default.
- W2072534308 cites W2011990999 @default.
- W2072534308 cites W2019695935 @default.
- W2072534308 cites W2021263280 @default.
- W2072534308 cites W2021457788 @default.
- W2072534308 cites W2022147927 @default.
- W2072534308 cites W2023596283 @default.
- W2072534308 cites W2025799912 @default.
- W2072534308 cites W2031799039 @default.
- W2072534308 cites W2032224049 @default.
- W2072534308 cites W2036402194 @default.
- W2072534308 cites W2037704831 @default.
- W2072534308 cites W2044756716 @default.
- W2072534308 cites W2046040325 @default.
- W2072534308 cites W2053884498 @default.
- W2072534308 cites W2056266836 @default.
- W2072534308 cites W2063216794 @default.
- W2072534308 cites W2066879412 @default.
- W2072534308 cites W2071880081 @default.
- W2072534308 cites W2077327464 @default.
- W2072534308 cites W2085570760 @default.
- W2072534308 cites W2085955241 @default.
- W2072534308 cites W2087028051 @default.
- W2072534308 cites W2092985709 @default.
- W2072534308 cites W2099039280 @default.
- W2072534308 cites W2112406610 @default.
- W2072534308 cites W2115960347 @default.
- W2072534308 cites W2123768693 @default.
- W2072534308 cites W2131624869 @default.
- W2072534308 cites W2139594259 @default.
- W2072534308 doi "https://doi.org/10.1073/pnas.0800405105" @default.
- W2072534308 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2492469" @default.
- W2072534308 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18653759" @default.
- W2072534308 hasPublicationYear "2008" @default.
- W2072534308 type Work @default.
- W2072534308 sameAs 2072534308 @default.
- W2072534308 citedByCount "91" @default.
- W2072534308 countsByYear W20725343082012 @default.
- W2072534308 countsByYear W20725343082013 @default.
- W2072534308 countsByYear W20725343082014 @default.
- W2072534308 countsByYear W20725343082015 @default.
- W2072534308 countsByYear W20725343082016 @default.
- W2072534308 countsByYear W20725343082017 @default.
- W2072534308 countsByYear W20725343082018 @default.
- W2072534308 countsByYear W20725343082019 @default.
- W2072534308 countsByYear W20725343082020 @default.
- W2072534308 countsByYear W20725343082021 @default.
- W2072534308 countsByYear W20725343082022 @default.
- W2072534308 countsByYear W20725343082023 @default.
- W2072534308 crossrefType "journal-article" @default.
- W2072534308 hasAuthorship W2072534308A5018859062 @default.
- W2072534308 hasAuthorship W2072534308A5047667506 @default.
- W2072534308 hasAuthorship W2072534308A5085362874 @default.
- W2072534308 hasBestOaLocation W20725343081 @default.
- W2072534308 hasConcept C104292427 @default.
- W2072534308 hasConcept C104317684 @default.
- W2072534308 hasConcept C121332964 @default.
- W2072534308 hasConcept C12554922 @default.
- W2072534308 hasConcept C147597530 @default.
- W2072534308 hasConcept C159467904 @default.
- W2072534308 hasConcept C185592680 @default.
- W2072534308 hasConcept C202878990 @default.
- W2072534308 hasConcept C204921945 @default.
- W2072534308 hasConcept C46141821 @default.
- W2072534308 hasConcept C521977710 @default.
- W2072534308 hasConcept C552990157 @default.
- W2072534308 hasConcept C55493867 @default.
- W2072534308 hasConcept C59593255 @default.
- W2072534308 hasConcept C8010536 @default.
- W2072534308 hasConcept C86803240 @default.
- W2072534308 hasConceptScore W2072534308C104292427 @default.
- W2072534308 hasConceptScore W2072534308C104317684 @default.
- W2072534308 hasConceptScore W2072534308C121332964 @default.
- W2072534308 hasConceptScore W2072534308C12554922 @default.
- W2072534308 hasConceptScore W2072534308C147597530 @default.
- W2072534308 hasConceptScore W2072534308C159467904 @default.