Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072541353> ?p ?o ?g. }
Showing items 1 to 53 of
53
with 100 items per page.
- W2072541353 endingPage "6" @default.
- W2072541353 startingPage "6" @default.
- W2072541353 abstract "To understand a neural circuit requires knowing the pattern of connectivity between its inputs and outputs. For example, the role of the retina in color vision depends on the pattern of connectivity between the lattice of cone photoreceptors and multiple types of retinal ganglion cells via the retinal circuitry. In the vertebrate nervous system, this kind of complete functional circuitry information has generally been out of reach. Here we report the first measurements of functional connectivity between input and output layers of the retina at single-cell resolution, and use the information to probe the neural computations subserving color vision. We employed a unique 512-electrode technology to record simultaneously from complete populations of the ganglion cell types which collectively mediate high-resolution vision in primates (midget, parasol, small bistratified). We then used fine-grained visual stimulation to separately identify the location and spectral type ([L]ong, [M]iddle or [S]hort-wavelength sensitive) of each cone photoreceptor providing input to each ganglion cell. The populations of ON and OFF midget and parasol cells each sampled essentially the complete population of L and M cones, with low redundancy. However, only OFF midget cells strongly sampled from S cones, an unexpected specificity. Statistical analysis revealed a non-random pattern of inputs from L and M cones to the receptive field centers of midget cells, while inputs to the receptive field surround were random. This specificity of cone inputs could not be explained by clumping in the cone mosaic, implying that developmental or adaptive mechanisms enhance opponent-color signals transmitted from retina to brain." @default.
- W2072541353 created "2016-06-24" @default.
- W2072541353 creator A5026936936 @default.
- W2072541353 date "2011-12-21" @default.
- W2072541353 modified "2023-09-28" @default.
- W2072541353 title "Functional connectivity in the retina at the elementary resolution of photoreceptors" @default.
- W2072541353 doi "https://doi.org/10.1167/11.15.6" @default.
- W2072541353 hasPublicationYear "2011" @default.
- W2072541353 type Work @default.
- W2072541353 sameAs 2072541353 @default.
- W2072541353 citedByCount "0" @default.
- W2072541353 crossrefType "journal-article" @default.
- W2072541353 hasAuthorship W2072541353A5026936936 @default.
- W2072541353 hasBestOaLocation W20725413531 @default.
- W2072541353 hasConcept C119088629 @default.
- W2072541353 hasConcept C144024400 @default.
- W2072541353 hasConcept C149923435 @default.
- W2072541353 hasConcept C169760540 @default.
- W2072541353 hasConcept C19071747 @default.
- W2072541353 hasConcept C2777093970 @default.
- W2072541353 hasConcept C2777624874 @default.
- W2072541353 hasConcept C2908647359 @default.
- W2072541353 hasConcept C86803240 @default.
- W2072541353 hasConceptScore W2072541353C119088629 @default.
- W2072541353 hasConceptScore W2072541353C144024400 @default.
- W2072541353 hasConceptScore W2072541353C149923435 @default.
- W2072541353 hasConceptScore W2072541353C169760540 @default.
- W2072541353 hasConceptScore W2072541353C19071747 @default.
- W2072541353 hasConceptScore W2072541353C2777093970 @default.
- W2072541353 hasConceptScore W2072541353C2777624874 @default.
- W2072541353 hasConceptScore W2072541353C2908647359 @default.
- W2072541353 hasConceptScore W2072541353C86803240 @default.
- W2072541353 hasIssue "15" @default.
- W2072541353 hasLocation W20725413531 @default.
- W2072541353 hasOpenAccess W2072541353 @default.
- W2072541353 hasPrimaryLocation W20725413531 @default.
- W2072541353 hasRelatedWork W107670920 @default.
- W2072541353 hasRelatedWork W1592219164 @default.
- W2072541353 hasRelatedWork W2047262515 @default.
- W2072541353 hasRelatedWork W2119226063 @default.
- W2072541353 hasRelatedWork W2130127881 @default.
- W2072541353 hasRelatedWork W2263928537 @default.
- W2072541353 hasRelatedWork W3024145095 @default.
- W2072541353 hasRelatedWork W3099546048 @default.
- W2072541353 hasRelatedWork W3174612157 @default.
- W2072541353 hasRelatedWork W68289718 @default.
- W2072541353 hasVolume "11" @default.
- W2072541353 isParatext "false" @default.
- W2072541353 isRetracted "false" @default.
- W2072541353 magId "2072541353" @default.
- W2072541353 workType "article" @default.