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- W2072582828 abstract "We examined possible genetic contributions to MK-801-elicited popping behavior in mice. MK-801-elicited popping behavior may represent a preclinical screening paradigm for identifying novel antipsychotic medications. Specifically, we studied the sensitivity of four inbred strains of mice (BALB/c, C57BL/6, AKR, and DBA/2) to MK-801-elicited popping behavior and compared their response to the outbred NIH Swiss strain in which the behavior was first characterized. The BALB/c strain was most sensitive to the elicitation of MK-801 induced popping behavior, whereas the other inbred strains were less sensitive than the outbred strain. The identification of strain differences in MK-801-elicited popping behavior suggests an important role for genetic factors in the elicitation of MK-801 popping behavior in mice." @default.
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- W2072582828 date "1997-05-01" @default.
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- W2072582828 title "Inbred Mouse Strains Differ in Sensitivity to “Popping” Behavior Elicited by MK-801" @default.
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- W2072582828 doi "https://doi.org/10.1016/s0091-3057(96)00347-4" @default.
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