Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072585510> ?p ?o ?g. }
Showing items 1 to 96 of
96
with 100 items per page.
- W2072585510 endingPage "276" @default.
- W2072585510 startingPage "273" @default.
- W2072585510 abstract "Scarce information is available on the real mechanism by which carbapenemes penetrate in Enterobacteriaceae, although a considerable amount of evidence suggests that in many species of this family the lack of certain outer membrane proteins is associated with the acquisition of resistance to these antibiotics. The existance of specific pathways for the carbapenems has never been demonstrated, although at times it has been postulated in both wild and mutant strains, on the basis of evident discordances between permeability patterns and suceptibility data. By using the Zimmerman and Rosselet technique, which requires the strain under investigation to harbor a suitable beta-lactamase, the permeability of intact Escherichia coli and Enterobacter cloacae cells to meropenem and imipenem was investigated by transferring a constructed vector carrying the carbapenem hydrolyzing CphA metallo-beta-lactamase gene into the parental strains and their porin-deficient mutants. Reduced amounts of nonspecific porins significantly reduced the penetration of both carbapenems. The virtual absence of porins caused the MICs of meropenem to increase, mostly in Enterobacter cloacae, while it did not affected the MICs of imipenem. No evidence of specific porin pathways of the type described in Pseudomonas aeruginosa was found." @default.
- W2072585510 created "2016-06-24" @default.
- W2072585510 creator A5026163102 @default.
- W2072585510 creator A5029943309 @default.
- W2072585510 creator A5036749845 @default.
- W2072585510 creator A5040953400 @default.
- W2072585510 date "1996-01-01" @default.
- W2072585510 modified "2023-10-01" @default.
- W2072585510 title "Diffusion of Carbapenems Through the Outer Membrane of Enterobacteriaceae and Correlation of Their Activities with Their Periplasmic Concentrations" @default.
- W2072585510 cites W1576608645 @default.
- W2072585510 cites W1915829691 @default.
- W2072585510 cites W1986790126 @default.
- W2072585510 cites W1991807646 @default.
- W2072585510 cites W2035450941 @default.
- W2072585510 cites W2039768473 @default.
- W2072585510 cites W2081593223 @default.
- W2072585510 cites W2114144362 @default.
- W2072585510 cites W2117378912 @default.
- W2072585510 cites W2148898597 @default.
- W2072585510 cites W2149492419 @default.
- W2072585510 doi "https://doi.org/10.1089/mdr.1996.2.273" @default.
- W2072585510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9158772" @default.
- W2072585510 hasPublicationYear "1996" @default.
- W2072585510 type Work @default.
- W2072585510 sameAs 2072585510 @default.
- W2072585510 citedByCount "10" @default.
- W2072585510 countsByYear W20725855102013 @default.
- W2072585510 countsByYear W20725855102018 @default.
- W2072585510 countsByYear W20725855102021 @default.
- W2072585510 countsByYear W20725855102022 @default.
- W2072585510 countsByYear W20725855102023 @default.
- W2072585510 crossrefType "journal-article" @default.
- W2072585510 hasAuthorship W2072585510A5026163102 @default.
- W2072585510 hasAuthorship W2072585510A5029943309 @default.
- W2072585510 hasAuthorship W2072585510A5036749845 @default.
- W2072585510 hasAuthorship W2072585510A5040953400 @default.
- W2072585510 hasConcept C104317684 @default.
- W2072585510 hasConcept C143065580 @default.
- W2072585510 hasConcept C146587185 @default.
- W2072585510 hasConcept C201663137 @default.
- W2072585510 hasConcept C2776685102 @default.
- W2072585510 hasConcept C2777317804 @default.
- W2072585510 hasConcept C2777402170 @default.
- W2072585510 hasConcept C2777637488 @default.
- W2072585510 hasConcept C2778910516 @default.
- W2072585510 hasConcept C2779375183 @default.
- W2072585510 hasConcept C2779631663 @default.
- W2072585510 hasConcept C501593827 @default.
- W2072585510 hasConcept C523546767 @default.
- W2072585510 hasConcept C54355233 @default.
- W2072585510 hasConcept C547475151 @default.
- W2072585510 hasConcept C55493867 @default.
- W2072585510 hasConcept C86803240 @default.
- W2072585510 hasConcept C89423630 @default.
- W2072585510 hasConcept C94665300 @default.
- W2072585510 hasConceptScore W2072585510C104317684 @default.
- W2072585510 hasConceptScore W2072585510C143065580 @default.
- W2072585510 hasConceptScore W2072585510C146587185 @default.
- W2072585510 hasConceptScore W2072585510C201663137 @default.
- W2072585510 hasConceptScore W2072585510C2776685102 @default.
- W2072585510 hasConceptScore W2072585510C2777317804 @default.
- W2072585510 hasConceptScore W2072585510C2777402170 @default.
- W2072585510 hasConceptScore W2072585510C2777637488 @default.
- W2072585510 hasConceptScore W2072585510C2778910516 @default.
- W2072585510 hasConceptScore W2072585510C2779375183 @default.
- W2072585510 hasConceptScore W2072585510C2779631663 @default.
- W2072585510 hasConceptScore W2072585510C501593827 @default.
- W2072585510 hasConceptScore W2072585510C523546767 @default.
- W2072585510 hasConceptScore W2072585510C54355233 @default.
- W2072585510 hasConceptScore W2072585510C547475151 @default.
- W2072585510 hasConceptScore W2072585510C55493867 @default.
- W2072585510 hasConceptScore W2072585510C86803240 @default.
- W2072585510 hasConceptScore W2072585510C89423630 @default.
- W2072585510 hasConceptScore W2072585510C94665300 @default.
- W2072585510 hasIssue "2" @default.
- W2072585510 hasLocation W20725855101 @default.
- W2072585510 hasLocation W20725855102 @default.
- W2072585510 hasOpenAccess W2072585510 @default.
- W2072585510 hasPrimaryLocation W20725855101 @default.
- W2072585510 hasRelatedWork W1964013076 @default.
- W2072585510 hasRelatedWork W2035201878 @default.
- W2072585510 hasRelatedWork W2072585510 @default.
- W2072585510 hasRelatedWork W2100193584 @default.
- W2072585510 hasRelatedWork W2103137511 @default.
- W2072585510 hasRelatedWork W2115999525 @default.
- W2072585510 hasRelatedWork W2136880793 @default.
- W2072585510 hasRelatedWork W2409675828 @default.
- W2072585510 hasRelatedWork W3151778090 @default.
- W2072585510 hasRelatedWork W145002129 @default.
- W2072585510 hasVolume "2" @default.
- W2072585510 isParatext "false" @default.
- W2072585510 isRetracted "false" @default.
- W2072585510 magId "2072585510" @default.
- W2072585510 workType "article" @default.