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- W2072608261 abstract "The detection of renovascular disease (RVD) has particular relevance in hypertensive patients (HP) who have symptoms of target organ damage. To evaluate the possibility of RVD in HP undergoing myocardial perfusion scintigraphy for chest pain symptoms, posterior renal images were obtained at 1-3 hours after TI-201 injection. Analog and computer images were obtained for 5 minutes in 45 HP; 12 patients with no history of hypertension or renal disease served as normal controls. For qualitative analysis, images were coded and read by three observers as to symmetry of renal uptake. Differential renal uptake of TI-201 (DRU) was quantitated on computer images. In normal controls, uptake was agreed on as symmetric. In HP, 6 patients had marked asymmetry of DRU and 4 had possibly significant asymmetry; 2 had decreased uptake in both kidneys suggesting bilateral RVD or nephrosclerosis. Objective correlation with DRU was obtained in 10 HP who had contrast angiography, confirming 4 cases of unilateral RVD and 2 of bilateral RVD. Thirteen patients also had renography with Tc-99m DTPA; differential renal function by this modality correlated well with DRU of TI-201 (r=0.98). Thus, DRU of TI-201 can be used as a supplement to myocardial scintigraphy to identify HP who require further evaluation and treatment of RVD." @default.
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- W2072608261 date "1990-02-01" @default.
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- W2072608261 title "Renal Uptake of TI-201 in Hypertensive Patients Undergoing Myocardial Perfusion Imaging" @default.
- W2072608261 doi "https://doi.org/10.1097/00003072-199002000-00005" @default.
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