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- W2072631373 abstract "Clinical utility of biodegradable magnesium implants is undermined by the untimely degradation of these materials in vivo. Their high corrosion rate leads to loss of mechanical integrity, peri-implant alkalization and localised accumulation of hydrogen gas. Biodegradable coatings were produced on pure magnesium using RF plasma polymerisation. A monoterpene alcohol with known anti-inflammatory and antibacterial properties was used as a polymer precursor. The addition of the polymeric layer was found to reduce the degradation rate of magnesium in simulated body fluid. The in vitro studies indicated good cytocompatibility of non-adherent THP-1 cells and mouse macrophage cells with the polymer, and the polymer coated sample. The viability of THP-1 cells was significantly improved when in contact with polymer encapsulated magnesium compared to unmodified samples. Collectively, these results suggest plasma enhanced polymer encapsulation of magnesium as a suitable method to control degradation kinetics of this biomaterial." @default.
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- W2072631373 date "2014-10-01" @default.
- W2072631373 modified "2023-10-06" @default.
- W2072631373 title "Polymer Encapsulation of Magnesium to Control Biodegradability and Biocompatibility" @default.
- W2072631373 doi "https://doi.org/10.1166/jnn.2014.9409" @default.
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