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- W2072632178 abstract "This magnetic resonance imaging (MRI)-based morphometric analysis of cortical topography in the human brain is based upon the segmentation and parcellation of volumetric T1-weighted MRI data for a set of 20 young adult brains including 10 males and 10 females. For the most part, each parcellation unit (PU) of the neocortex corresponds to a single or a portion of a single gyrus. The volumes of each PU were computed for each brain. Subsets of PUs were also grouped so as to represent the neocortex for the frontal, temporal, parietal and occipital lobes. The coefficient of variation of the mean volume of total neocortex and that of the neocortex assigned to individual lobes cluster around 10%, whereas that of neocortex assigned to the individual gyri (PU) is more than twice that value. Approximately 80% of the total variance in gyral volume arises from determinants interactive for individual and specific gyri, while only approximately 10% of the total variance appears to be a reflection of uniform scaling to total neocortical volume. Sexual dimorphism contributes a pervasive though relatively small component of this variance. These results have implications for the study of structure-function correlation, and the proper statistical methods of handling volumetric data in morphometric studies. In addition, the nature of the covariance structure of the data will lead to future hypotheses regarding the relationships between the various potential genetic and epigenetic gyral influencing factors." @default.
- W2072632178 created "2016-06-24" @default.
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- W2072632178 date "1998-06-01" @default.
- W2072632178 modified "2023-10-11" @default.
- W2072632178 title "Gyri of the human neocortex: an MRI-based analysis of volume and variance" @default.
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- W2072632178 doi "https://doi.org/10.1093/cercor/8.4.372" @default.
- W2072632178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9651132" @default.
- W2072632178 hasPublicationYear "1998" @default.
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