FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072639782> ?p ?o ?g. }

• W2072639782 endingPage "159" @default.
• W2072639782 startingPage "159" @default.
• W2072639782 abstract "Echinocandins represent the newest class of antifungal agents. Currently, three echinocandins, anidulafungin, caspofungin and micafungin are licensed for clinical use in various indications. They act as inhibitors of β-(1,3)-glucan synthesis in the fungal cell wall and have a favorable pharmacological profile. They have a broad spectrum of activity against all Candida species. Higher MIC's have been observed against C. parapsilosis and C. guilliermondii. Data from clinical trials for invasive Candida infections / candidaemia suggest that the clinical outcome of patients treated with either drug may be very similar. A comparison has been done between caspofungin and micafungin but for anidulafungin a comparative trial with another echinocandin is still lacking. All three drugs are highly effective if not superior to treatment with either fluconazole or Amphotericin B, particularly in well-defined clinical settings such as invasive Candida infections, Candida oesophagitis and candidaemia. Differences between the three echinocandins with regard to the route of metabolism, requirement for a loading dose, dose adjustment in patients with moderate to severe hepatic disease and different dosing schedules for different types of Candida infections have to be considered. Relevant drug-drug interactions of Caspofungin and Micafungin are minimal. Anidulafungin has no significant drug interactions at all. However, echinocandins are available only for intravenous use. All three agents have an excellent safety profile." @default.
• W2072639782 created "2016-06-24" @default.
• W2072639782 creator A5002280296 @default.
• W2072639782 creator A5066883490 @default.
• W2072639782 date "2011-01-01" @default.
• W2072639782 modified "2023-10-14" @default.
• W2072639782 title "Pharmacology and metabolism of anidulafungin, caspofungin and micafungin in the treatment of invasive candidosis - review of the literature" @default.
• W2072639782 cites W1906221324 @default.
• W2072639782 cites W1976245670 @default.
• W2072639782 cites W1976510938 @default.
• W2072639782 cites W1982075188 @default.
• W2072639782 cites W1985135345 @default.
• W2072639782 cites W1986828869 @default.
• W2072639782 cites W1987292873 @default.
• W2072639782 cites W1990632892 @default.
• W2072639782 cites W1992373719 @default.
• W2072639782 cites W1994613828 @default.
• W2072639782 cites W1997208316 @default.
• W2072639782 cites W2000232926 @default.
• W2072639782 cites W2004503571 @default.
• W2072639782 cites W2006277360 @default.
• W2072639782 cites W2014557179 @default.
• W2072639782 cites W2019847904 @default.
• W2072639782 cites W2034599708 @default.
• W2072639782 cites W2046768677 @default.
• W2072639782 cites W2050080237 @default.
• W2072639782 cites W2079062174 @default.
• W2072639782 cites W2096246644 @default.
• W2072639782 cites W2097132369 @default.
• W2072639782 cites W2097394217 @default.
• W2072639782 cites W2099951777 @default.
• W2072639782 cites W2100354457 @default.
• W2072639782 cites W2105160584 @default.
• W2072639782 cites W2108491966 @default.
• W2072639782 cites W2108739140 @default.
• W2072639782 cites W2109890308 @default.
• W2072639782 cites W2114146849 @default.
• W2072639782 cites W2114785045 @default.
• W2072639782 cites W2118776720 @default.
• W2072639782 cites W2121247465 @default.
• W2072639782 cites W2121300089 @default.
• W2072639782 cites W2123557864 @default.
• W2072639782 cites W2124127923 @default.
• W2072639782 cites W2126319933 @default.
• W2072639782 cites W2127695411 @default.
• W2072639782 cites W2128309368 @default.
• W2072639782 cites W2130655869 @default.
• W2072639782 cites W2133327568 @default.
• W2072639782 cites W2133731564 @default.
• W2072639782 cites W2135458701 @default.
• W2072639782 cites W2138120954 @default.
• W2072639782 cites W2138348369 @default.
• W2072639782 cites W2144376822 @default.
• W2072639782 cites W2146907515 @default.
• W2072639782 cites W2147556278 @default.
• W2072639782 cites W2147723584 @default.
• W2072639782 cites W2150428940 @default.
• W2072639782 cites W2153828715 @default.
• W2072639782 cites W2154030470 @default.
• W2072639782 cites W2154056008 @default.
• W2072639782 cites W2154403663 @default.
• W2072639782 cites W2156082251 @default.
• W2072639782 cites W2157766752 @default.
• W2072639782 cites W2158530375 @default.
• W2072639782 cites W2160026917 @default.
• W2072639782 cites W2163769057 @default.
• W2072639782 cites W2165491490 @default.
• W2072639782 cites W2165781451 @default.
• W2072639782 cites W2165877695 @default.
• W2072639782 cites W2167412063 @default.
• W2072639782 cites W2168334830 @default.
• W2072639782 cites W2171155970 @default.
• W2072639782 cites W2172274380 @default.
• W2072639782 cites W2917702355 @default.
• W2072639782 cites W4253591609 @default.
• W2072639782 doi "https://doi.org/10.1186/2047-783x-16-4-159" @default.
• W2072639782 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3352072" @default.
• W2072639782 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21486730" @default.
• W2072639782 hasPublicationYear "2011" @default.
• W2072639782 type Work @default.
• W2072639782 sameAs 2072639782 @default.
• W2072639782 citedByCount "118" @default.
• W2072639782 countsByYear W20726397822012 @default.
• W2072639782 countsByYear W20726397822013 @default.
• W2072639782 countsByYear W20726397822014 @default.
• W2072639782 countsByYear W20726397822015 @default.
• W2072639782 countsByYear W20726397822016 @default.
• W2072639782 countsByYear W20726397822017 @default.
• W2072639782 countsByYear W20726397822018 @default.
• W2072639782 countsByYear W20726397822019 @default.
• W2072639782 countsByYear W20726397822020 @default.
• W2072639782 countsByYear W20726397822021 @default.
• W2072639782 countsByYear W20726397822022 @default.
• W2072639782 countsByYear W20726397822023 @default.
• W2072639782 crossrefType "journal-article" @default.
• W2072639782 hasAuthorship W2072639782A5002280296 @default.
• W2072639782 hasAuthorship W2072639782A5066883490 @default.
• W2072639782 hasBestOaLocation W20726397821 @default.

• next