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- W2072669401 abstract "Background: Irritable bowel syndrome remains the commonest reason for referral to a gastroenterology clinic. Patients with irritable bowel syndrome are frequently advised to increase their intake of bran fibre, despite inconclusive experimental evidence of benefit. Methods: The effect of dietary supplementation with a bolus of bran fibre (12 g/day) was studied in a block-randomized, placebo-controlled, crossover study of 80 patients with irritable bowel syndrome referred to a District General Hospital outpatient clinic. Comparison of the benefits of bran and placebo was based upon personal assessment of individual and overall symptom profiles, determined from a simple daily symptom score and post-treatment interview. Results: Overall symptomatic improvement was reported with bran by 52% and with placebo by 54% of patients. Bran supplementation was no more effective than placebo in improving individual symptoms of irritable bowel syndrome, and for wind-related symptoms it was significantly less effective (P < 0.001). Conclusion: Dietary supplementation with bran is of no value in the treatment of patients with irritable bowel syndrome referred to a hospital clinic." @default.
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- W2072669401 date "2007-03-31" @default.
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- W2072669401 title "Bran supplementation in the treatment of irritable bowel sgndrome" @default.
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- W2072669401 doi "https://doi.org/10.1111/j.1365-2036.1994.tb00323.x" @default.
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