FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072671231> ?p ?o ?g. }

• W2072671231 endingPage "115" @default.
• W2072671231 startingPage "108" @default.
• W2072671231 abstract "Background The neuroendocrine cells of the human prostate have been related to proliferative disorders such as prostatic cancer. Their origin, distribution, and development have therefore been studied and discussed in terms of current stem cell concepts in the prostate. Methods Prostatic tissue specimens (n = 20) from human fetuses (n = 8), prepubertal and pubertal children (n = 8) and mature men (n = 4) were studied immunohistochemically using antibodies directed against neuroendocrine, epithelial as well as secretory markers. Semiquantitative computer-assisted evaluation of different epithelial and stromal components based on stereological principles was performed on azan-stained sections representative of all developmental stages. Results By the end of gestational Week 9, neuroendocrine (NE) cells appear in the epithelium of the urogenital sinus and are subsequently closely associated with the formation of urethral prostatic buds. The fetal and postnatal distribution pattern of NE cells within the gland is characterized by a relatively constant number of cells per gland similar to prostatic smooth muscle cells. Likewise, a density gradient exists with the highest density in the large collicular ducts and almost no NE cells in subcapsular peripheral acini. In peripheral ducts, the distribution is random. Maturation of the NE cells precedes that of the secretory cells by about 10–16 years. Conclusions A second prostatic stem cell lineage, different from the urogenital sinus (UGS)-lineage is hypothesized originating from immature neuroendocrine cells. Being morphologically indistinguishable from the UGS-derived prostatic secretory cell lineage, it gives rise to neuroendocrine cells. Their presence is apparently important for proliferation regulation of the UGS-derived lineage of the prostate. Prostate 46:108–115, 2001. © 2001 Wiley-Liss, Inc." @default.
• W2072671231 created "2016-06-24" @default.
• W2072671231 creator A5003532370 @default.
• W2072671231 creator A5015634061 @default.
• W2072671231 creator A5043570965 @default.
• W2072671231 creator A5057676572 @default.
• W2072671231 creator A5067715842 @default.
• W2072671231 creator A5084553993 @default.
• W2072671231 date "2001-01-01" @default.
• W2072671231 modified "2023-10-04" @default.
• W2072671231 title "Semiquantitative morphology of human prostatic development and regional distribution of prostatic neuroendocrine cells" @default.
• W2072671231 cites W1973609567 @default.
• W2072671231 cites W1994355495 @default.
• W2072671231 cites W1999397704 @default.
• W2072671231 cites W1999864225 @default.
• W2072671231 cites W2000320905 @default.
• W2072671231 cites W2015358216 @default.
• W2072671231 cites W2015387952 @default.
• W2072671231 cites W2015877307 @default.
• W2072671231 cites W2019970977 @default.
• W2072671231 cites W2020442769 @default.
• W2072671231 cites W2044189638 @default.
• W2072671231 cites W2046063243 @default.
• W2072671231 cites W2054425455 @default.
• W2072671231 cites W2056733481 @default.
• W2072671231 cites W2098882558 @default.
• W2072671231 cites W2105536309 @default.
• W2072671231 cites W2107152318 @default.
• W2072671231 cites W2132728194 @default.
• W2072671231 cites W2145302607 @default.
• W2072671231 cites W2423393228 @default.
• W2072671231 cites W4300711378 @default.
• W2072671231 doi "https://doi.org/10.1002/1097-0045(20010201)46:2<108::aid-pros1014>3.0.co;2-9" @default.
• W2072671231 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11170138" @default.
• W2072671231 hasPublicationYear "2001" @default.
• W2072671231 type Work @default.
• W2072671231 sameAs 2072671231 @default.
• W2072671231 citedByCount "35" @default.
• W2072671231 countsByYear W20726712312012 @default.
• W2072671231 countsByYear W20726712312013 @default.
• W2072671231 countsByYear W20726712312017 @default.
• W2072671231 countsByYear W20726712312019 @default.
• W2072671231 countsByYear W20726712312020 @default.
• W2072671231 countsByYear W20726712312022 @default.
• W2072671231 crossrefType "journal-article" @default.
• W2072671231 hasAuthorship W2072671231A5003532370 @default.
• W2072671231 hasAuthorship W2072671231A5015634061 @default.
• W2072671231 hasAuthorship W2072671231A5043570965 @default.
• W2072671231 hasAuthorship W2072671231A5057676572 @default.
• W2072671231 hasAuthorship W2072671231A5067715842 @default.
• W2072671231 hasAuthorship W2072671231A5084553993 @default.
• W2072671231 hasConcept C121608353 @default.
• W2072671231 hasConcept C126322002 @default.
• W2072671231 hasConcept C134018914 @default.
• W2072671231 hasConcept C142724271 @default.
• W2072671231 hasConcept C16930146 @default.
• W2072671231 hasConcept C172680121 @default.
• W2072671231 hasConcept C204232928 @default.
• W2072671231 hasConcept C2776235491 @default.
• W2072671231 hasConcept C2777858994 @default.
• W2072671231 hasConcept C2779234561 @default.
• W2072671231 hasConcept C2780192828 @default.
• W2072671231 hasConcept C2780341458 @default.
• W2072671231 hasConcept C28328180 @default.
• W2072671231 hasConcept C529295009 @default.
• W2072671231 hasConcept C54355233 @default.
• W2072671231 hasConcept C71924100 @default.
• W2072671231 hasConcept C86803240 @default.
• W2072671231 hasConcept C95444343 @default.
• W2072671231 hasConceptScore W2072671231C121608353 @default.
• W2072671231 hasConceptScore W2072671231C126322002 @default.
• W2072671231 hasConceptScore W2072671231C134018914 @default.
• W2072671231 hasConceptScore W2072671231C142724271 @default.
• W2072671231 hasConceptScore W2072671231C16930146 @default.
• W2072671231 hasConceptScore W2072671231C172680121 @default.
• W2072671231 hasConceptScore W2072671231C204232928 @default.
• W2072671231 hasConceptScore W2072671231C2776235491 @default.
• W2072671231 hasConceptScore W2072671231C2777858994 @default.
• W2072671231 hasConceptScore W2072671231C2779234561 @default.
• W2072671231 hasConceptScore W2072671231C2780192828 @default.
• W2072671231 hasConceptScore W2072671231C2780341458 @default.
• W2072671231 hasConceptScore W2072671231C28328180 @default.
• W2072671231 hasConceptScore W2072671231C529295009 @default.
• W2072671231 hasConceptScore W2072671231C54355233 @default.
• W2072671231 hasConceptScore W2072671231C71924100 @default.
• W2072671231 hasConceptScore W2072671231C86803240 @default.
• W2072671231 hasConceptScore W2072671231C95444343 @default.
• W2072671231 hasIssue "2" @default.
• W2072671231 hasLocation W20726712311 @default.
• W2072671231 hasLocation W20726712312 @default.
• W2072671231 hasOpenAccess W2072671231 @default.
• W2072671231 hasPrimaryLocation W20726712311 @default.
• W2072671231 hasRelatedWork W1973833989 @default.
• W2072671231 hasRelatedWork W1993795923 @default.
• W2072671231 hasRelatedWork W2002562299 @default.
• W2072671231 hasRelatedWork W2091151050 @default.
• W2072671231 hasRelatedWork W2096397790 @default.
• W2072671231 hasRelatedWork W2131811784 @default.

• next