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• W2072703944 abstract "Despite interest in causes of dementia in older persons, particularly in post-menopausal women, it is unclear whether hormone replacement therapy (HRT) is a risk factor.To assess cognitive function in post-menopausal women with high educational status receiving HRT, compared to non-users.Cognitive functioning was assessed with in women aged 55-60 years with at least university-level education, using the Mindstreams system, a computerized cognitive battery with multiple domains.Of 165 women meeting the inclusion/exclusion criteria, 82 women (49.7%) declined participation. Of the remaining 83, 40 (48.2%) had never received HRT; the remainder was divided into women receiving 5-9 years HRT (n = 29)versus those with >or=10 years HRT (n = 11). There were no statistically significant differences between HRT users and non-users in global scores or sub-domains of cognitive functioning, and no difference between those women receiving HRT for 5-9 years vs. >or=10 years.Long-term HRT does not appear to impair cognitive functioning in highly-educated women. Recommendations regarding post-menopausal HRT should be made on an individual basis." @default.
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• W2072703944 date "2007-06-05" @default.
• W2072703944 modified "2023-09-25" @default.
• W2072703944 title "The effect of hormone replacement therapy on cognitive function in post-menopausal women" @default.
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• W2072703944 doi "https://doi.org/10.1093/qjmed/hcm065" @default.
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