FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072732232> ?p ?o ?g. }

• W2072732232 endingPage "28" @default.
• W2072732232 startingPage "23" @default.
• W2072732232 abstract "We studied Haemophilus influenzae type b meningitis in 68 patients to evaluate whether quantitative determination of PRP in body fluids obtained at admission or measurement of the duration of its presence helped identify patients at risk for complications. Geometric mean admission PRP concentrations in CSF, blood, and urine increased with severity of disease, but individual values varied greatly. Measurements of the duration of antigenemia and antigenuria also varied widely and were best predicted by the admission or peak PRP concentration. The mean duration of both antigenemia and antigenuria increased with severity of disease. In contrast, the elimination half-life of PRP did not differ significantly with severity of hospital course, peak PRP concentration in blood or urine, or patient age. Clearance from CSF could not be accurately assessed, but PRP was detectable in only six of 41 patients in whom spinal fluid was obtained after the eighth day of hospitalization; all had complicated courses. Although latex particle agglutination assay is a valuable aid in rapid diagnosis of invasive Hib infections, the predictive value of antigen quantitation at admission and the determination of its duration in body fluids is limited by the wide range of observed values. We studied Haemophilus influenzae type b meningitis in 68 patients to evaluate whether quantitative determination of PRP in body fluids obtained at admission or measurement of the duration of its presence helped identify patients at risk for complications. Geometric mean admission PRP concentrations in CSF, blood, and urine increased with severity of disease, but individual values varied greatly. Measurements of the duration of antigenemia and antigenuria also varied widely and were best predicted by the admission or peak PRP concentration. The mean duration of both antigenemia and antigenuria increased with severity of disease. In contrast, the elimination half-life of PRP did not differ significantly with severity of hospital course, peak PRP concentration in blood or urine, or patient age. Clearance from CSF could not be accurately assessed, but PRP was detectable in only six of 41 patients in whom spinal fluid was obtained after the eighth day of hospitalization; all had complicated courses. Although latex particle agglutination assay is a valuable aid in rapid diagnosis of invasive Hib infections, the predictive value of antigen quantitation at admission and the determination of its duration in body fluids is limited by the wide range of observed values." @default.
• W2072732232 created "2016-06-24" @default.
• W2072732232 creator A5013602212 @default.
• W2072732232 creator A5020535446 @default.
• W2072732232 creator A5042017706 @default.
• W2072732232 creator A5063276569 @default.
• W2072732232 creator A5079302486 @default.
• W2072732232 date "1984-01-01" @default.
• W2072732232 modified "2023-09-26" @default.
• W2072732232 title "Value of antigen quantitation in Haemophilus influenzae type b meningitis" @default.
• W2072732232 cites W1524463238 @default.
• W2072732232 cites W1534802414 @default.
• W2072732232 cites W1846854606 @default.
• W2072732232 cites W1978138156 @default.
• W2072732232 cites W1982272459 @default.
• W2072732232 cites W1983750209 @default.
• W2072732232 cites W2004563770 @default.
• W2072732232 cites W2006664151 @default.
• W2072732232 cites W2015556298 @default.
• W2072732232 cites W2028532151 @default.
• W2072732232 cites W2031138522 @default.
• W2072732232 cites W2083172237 @default.
• W2072732232 doi "https://doi.org/10.1016/s0022-3476(84)80583-1" @default.
• W2072732232 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6690672" @default.
• W2072732232 hasPublicationYear "1984" @default.
• W2072732232 type Work @default.
• W2072732232 sameAs 2072732232 @default.
• W2072732232 citedByCount "12" @default.
• W2072732232 crossrefType "journal-article" @default.
• W2072732232 hasAuthorship W2072732232A5013602212 @default.
• W2072732232 hasAuthorship W2072732232A5020535446 @default.
• W2072732232 hasAuthorship W2072732232A5042017706 @default.
• W2072732232 hasAuthorship W2072732232A5063276569 @default.
• W2072732232 hasAuthorship W2072732232A5079302486 @default.
• W2072732232 hasConcept C126322002 @default.
• W2072732232 hasConcept C141071460 @default.
• W2072732232 hasConcept C159654299 @default.
• W2072732232 hasConcept C203014093 @default.
• W2072732232 hasConcept C2776735168 @default.
• W2072732232 hasConcept C2776925733 @default.
• W2072732232 hasConcept C2779651940 @default.
• W2072732232 hasConcept C2780026642 @default.
• W2072732232 hasConcept C2781026528 @default.
• W2072732232 hasConcept C37977956 @default.
• W2072732232 hasConcept C501593827 @default.
• W2072732232 hasConcept C71924100 @default.
• W2072732232 hasConcept C86803240 @default.
• W2072732232 hasConcept C89423630 @default.
• W2072732232 hasConcept C90924648 @default.
• W2072732232 hasConceptScore W2072732232C126322002 @default.
• W2072732232 hasConceptScore W2072732232C141071460 @default.
• W2072732232 hasConceptScore W2072732232C159654299 @default.
• W2072732232 hasConceptScore W2072732232C203014093 @default.
• W2072732232 hasConceptScore W2072732232C2776735168 @default.
• W2072732232 hasConceptScore W2072732232C2776925733 @default.
• W2072732232 hasConceptScore W2072732232C2779651940 @default.
• W2072732232 hasConceptScore W2072732232C2780026642 @default.
• W2072732232 hasConceptScore W2072732232C2781026528 @default.
• W2072732232 hasConceptScore W2072732232C37977956 @default.
• W2072732232 hasConceptScore W2072732232C501593827 @default.
• W2072732232 hasConceptScore W2072732232C71924100 @default.
• W2072732232 hasConceptScore W2072732232C86803240 @default.
• W2072732232 hasConceptScore W2072732232C89423630 @default.
• W2072732232 hasConceptScore W2072732232C90924648 @default.
• W2072732232 hasIssue "1" @default.
• W2072732232 hasLocation W20727322321 @default.
• W2072732232 hasLocation W20727322322 @default.
• W2072732232 hasOpenAccess W2072732232 @default.
• W2072732232 hasPrimaryLocation W20727322321 @default.
• W2072732232 hasRelatedWork W158623349 @default.
• W2072732232 hasRelatedWork W1974406051 @default.
• W2072732232 hasRelatedWork W2004038976 @default.
• W2072732232 hasRelatedWork W2049682764 @default.
• W2072732232 hasRelatedWork W2058074801 @default.
• W2072732232 hasRelatedWork W2061102555 @default.
• W2072732232 hasRelatedWork W2121172725 @default.
• W2072732232 hasRelatedWork W2408903635 @default.
• W2072732232 hasRelatedWork W2411751985 @default.
• W2072732232 hasRelatedWork W2417895164 @default.
• W2072732232 hasVolume "104" @default.
• W2072732232 isParatext "false" @default.
• W2072732232 isRetracted "false" @default.
• W2072732232 magId "2072732232" @default.
• W2072732232 workType "article" @default.