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• W2072742806 abstract "<h3>Background:</h3> Nausea and vomiting in early pregnancy (NVEP) is commonly encountered in family medicine. Ginger (Zingiber officinale) is a popular nonpharmacological treatment but consensus of its use is lacking. <h3>Methods:</h3> We conducted a meta-analysis of clinical trials using ginger for NVEP as published in PubMed and EMBASE, CINAHL, Cochrane Library, and all EBM reviews. Studies satisfying 3 criteria were selected: (1) randomized placebo-controlled design; (2) use of ginger or Z. officinale; and (3) extractable data on improvement in NVEP. Data were synthesized into pooled odd ratios based on the random effects model, and results were tabulated with the aid of Forest plots. <h3>Results:</h3> We identified 135 potentially relevant records; only 6 studies met the final criteria. Of the total 508 subjects, 256 and 252 subjects were randomly assigned to receive ginger and placebo, respectively. The use of ginger (∼1 g daily) for at least 4 days is associated with a 5-fold likelihood of improvement in NVEP. Heterogeneity among the clinical studies were acknowledged in the final interpretation of results. <h3>Conclusions:</h3> Despite the widespread use of ginger in the diet, its clinic value and safety profile in treating NVEP is still unknown. Our meta-analysis suggests that ginger is an effective nonpharmacological treatment for NVEP." @default.
• W2072742806 created "2016-06-24" @default.
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• W2072742806 creator A5055027447 @default.
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• W2072742806 date "2014-01-01" @default.
• W2072742806 modified "2023-10-16" @default.
• W2072742806 title "Effects of Ginger for Nausea and Vomiting in Early Pregnancy: A Meta-Analysis" @default.
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• W2072742806 doi "https://doi.org/10.3122/jabfm.2014.01.130167" @default.
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