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- W2072755978 abstract "One hundred twenty-six liver and 2 combined liver/kidney transplants were included in data analysis. In 101 patients the primary immunosuppression was tacrolimus (TAC) and in 27 it was cyclosporine (CsA). A total of 32 psychiatric complications were seen in 27 patients (21%). There were 22 male and 5 female patients with a mean age of 47 (range 21 to 65). In 21 (62.8%) cases the onset was within the first 3 months. Types of complications included depression, 14 (44%); insomnia, 5 (16%); anxiety, 4 (13%); psychosis, 3 (9%); drug seeking behavior, 2 (6%); conduct changes, 2 (6%); mood swings, 1 (3%); and anorexia 1 (3%). Although 11 out of 63 patients with hepatitis C as the etiology of liver disease developed depression (17.4%), the number of patients developing depression was 3 out of 65 (4.6%) in the group of patients whose etiology was not hepatitis C (P .02). Twenty-two out of 101 patients (21.7%) receiving TAC and 5 out of 27 (18.5%) patients receiving CsA as the primary immunosuppressant developed psychiatric complications (P .7). CONCLUSIONS" @default.
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- W2072755978 date "2001-11-01" @default.
- W2072755978 modified "2023-10-17" @default.
- W2072755978 title "Psychiatric complications after liver transplantation" @default.
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- W2072755978 doi "https://doi.org/10.1016/s0041-1345(01)02508-8" @default.
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