Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072760254> ?p ?o ?g. }
- W2072760254 endingPage "328" @default.
- W2072760254 startingPage "321" @default.
- W2072760254 abstract "The innate immune system has evolved under selective pressure since the radiation of multicellular life approximately 600 million years ago. Because of this long history, innate immune mechanisms found in modern eukaryotic organisms today are highly complex but yet built from common molecular strategies. It is now clear that evolution has selected a conserved set of antimicrobial peptides as well as pattern-recognition receptors (PRRs) that initiate cellular-based signals as a first line of defense against invading pathogens. Conversely, microbial pathogens employ their own strategies in order to evade, inhibit, or otherwise manipulate the innate immune response. Here, we discuss recent discoveries that have changed our view of immune modulatory mechanisms employed by bacterial pathogens, focusing specifically on the initial sites of microbial recognition and extending to host cellular signal transduction, proinflammatory cytokine production, and alteration of protein trafficking and secretion." @default.
- W2072760254 created "2016-06-24" @default.
- W2072760254 creator A5024512046 @default.
- W2072760254 creator A5060915155 @default.
- W2072760254 date "2014-04-01" @default.
- W2072760254 modified "2023-10-13" @default.
- W2072760254 title "Bacteria Fighting Back: How Pathogens Target and Subvert the Host Innate Immune System" @default.
- W2072760254 cites W1483162601 @default.
- W2072760254 cites W1567210565 @default.
- W2072760254 cites W1577019338 @default.
- W2072760254 cites W1587370883 @default.
- W2072760254 cites W1891980138 @default.
- W2072760254 cites W1970121815 @default.
- W2072760254 cites W1970953122 @default.
- W2072760254 cites W1972169896 @default.
- W2072760254 cites W1974405307 @default.
- W2072760254 cites W1979630091 @default.
- W2072760254 cites W1982477315 @default.
- W2072760254 cites W1983332448 @default.
- W2072760254 cites W1985193810 @default.
- W2072760254 cites W1986035238 @default.
- W2072760254 cites W1988752967 @default.
- W2072760254 cites W1994098589 @default.
- W2072760254 cites W1997648709 @default.
- W2072760254 cites W1999410205 @default.
- W2072760254 cites W2001366460 @default.
- W2072760254 cites W2005943324 @default.
- W2072760254 cites W2015532987 @default.
- W2072760254 cites W2019122148 @default.
- W2072760254 cites W2021155705 @default.
- W2072760254 cites W2023988408 @default.
- W2072760254 cites W2027300067 @default.
- W2072760254 cites W2027493889 @default.
- W2072760254 cites W2029951660 @default.
- W2072760254 cites W2033098156 @default.
- W2072760254 cites W2034829165 @default.
- W2072760254 cites W2035806681 @default.
- W2072760254 cites W2038143978 @default.
- W2072760254 cites W2052874989 @default.
- W2072760254 cites W2055408817 @default.
- W2072760254 cites W2059408709 @default.
- W2072760254 cites W2061552846 @default.
- W2072760254 cites W2063130294 @default.
- W2072760254 cites W2066507447 @default.
- W2072760254 cites W2066822302 @default.
- W2072760254 cites W2079412449 @default.
- W2072760254 cites W2094243402 @default.
- W2072760254 cites W2094863064 @default.
- W2072760254 cites W2096227166 @default.
- W2072760254 cites W2098875897 @default.
- W2072760254 cites W2101355256 @default.
- W2072760254 cites W2102550380 @default.
- W2072760254 cites W2114335580 @default.
- W2072760254 cites W2114737175 @default.
- W2072760254 cites W2124081239 @default.
- W2072760254 cites W2129319296 @default.
- W2072760254 cites W2131215673 @default.
- W2072760254 cites W2145638464 @default.
- W2072760254 cites W2155538302 @default.
- W2072760254 cites W2157116022 @default.
- W2072760254 cites W2157740852 @default.
- W2072760254 cites W2158903248 @default.
- W2072760254 doi "https://doi.org/10.1016/j.molcel.2014.03.010" @default.
- W2072760254 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4023866" @default.
- W2072760254 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24766896" @default.
- W2072760254 hasPublicationYear "2014" @default.
- W2072760254 type Work @default.
- W2072760254 sameAs 2072760254 @default.
- W2072760254 citedByCount "158" @default.
- W2072760254 countsByYear W20727602542014 @default.
- W2072760254 countsByYear W20727602542015 @default.
- W2072760254 countsByYear W20727602542016 @default.
- W2072760254 countsByYear W20727602542017 @default.
- W2072760254 countsByYear W20727602542018 @default.
- W2072760254 countsByYear W20727602542019 @default.
- W2072760254 countsByYear W20727602542020 @default.
- W2072760254 countsByYear W20727602542021 @default.
- W2072760254 countsByYear W20727602542022 @default.
- W2072760254 countsByYear W20727602542023 @default.
- W2072760254 crossrefType "journal-article" @default.
- W2072760254 hasAuthorship W2072760254A5024512046 @default.
- W2072760254 hasAuthorship W2072760254A5060915155 @default.
- W2072760254 hasBestOaLocation W20727602541 @default.
- W2072760254 hasConcept C104317684 @default.
- W2072760254 hasConcept C111289621 @default.
- W2072760254 hasConcept C136449434 @default.
- W2072760254 hasConcept C164027704 @default.
- W2072760254 hasConcept C203014093 @default.
- W2072760254 hasConcept C2776914184 @default.
- W2072760254 hasConcept C49039625 @default.
- W2072760254 hasConcept C4937899 @default.
- W2072760254 hasConcept C540938839 @default.
- W2072760254 hasConcept C54355233 @default.
- W2072760254 hasConcept C55493867 @default.
- W2072760254 hasConcept C62478195 @default.
- W2072760254 hasConcept C74318829 @default.
- W2072760254 hasConcept C86803240 @default.
- W2072760254 hasConcept C8891405 @default.