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• W2072773893 abstract "In this study, the membrane lipids of B. burgdorferi were separated into 16 fractions; the components in each fraction were identified, and the immunogenicity of each fraction was determined by ELISA using sera from Lyme disease patients. Only the 2 glycolipids, acylated cholesteryl galactoside (ACG, BbGL-I) and monogalactosyl diacylglycerol (MgalD, BbGL-II), were immunogenic. Early in the infection, 24 of 84 patients (29%) who were convalescent from erythema migrans and 19 of the 35 patients (54%) with neuroborreliosis had weak IgG responses to purified MgalD, and a smaller percentage of patients had early responses to synthetic ACG. However, almost all of 75 patients with Lyme arthritis, a late disease manifestation, had strong IgG reactivity with both glycolipids. Thus, almost all patients with Lyme arthritis have strong IgG antibody responses to B. burgdorferi glycolipid antigens." @default.
• W2072773893 created "2016-06-24" @default.
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• W2072773893 date "2009-07-01" @default.
• W2072773893 modified "2023-09-27" @default.
• W2072773893 title "Strong IgG antibody responses to Borrelia burgdorferi glycolipids in patients with Lyme arthritis, a late manifestation of the infection" @default.
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• W2072773893 doi "https://doi.org/10.1016/j.clim.2009.03.510" @default.
• W2072773893 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2752957" @default.
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