FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072783248> ?p ?o ?g. }

• W2072783248 endingPage "7159" @default.
• W2072783248 startingPage "7153" @default.
• W2072783248 abstract "Positron emission tomography (PET) imaging is increasingly used to confirm localization of (90)Y microspheres in the treatment of liver cancer. The aim of this work was to evaluate the quantification of (90)Y PET data on a current generation time-of-flight extended axial field-of-view PET∕CT camera.The International Electrotechnical Commission (IEC) body phantom was used to image six spheres of varying diameters containing a high concentration of (90)Y solution in a lower concentration background. Multiple PET studies were acquired of the phantom over a number of days during decay. The effect of reconstruction parameters in OSEM was evaluated both qualitatively and quantitatively. Expected values of total phantom activity, hot-sphere, and background concentration were compared to measured values from the reconstructed data as well as misplaced events in a cold insert. The partial volume effect was measured and the effects of time-of-flight during reconstruction on hot contrast recovery and background variability were evaluated according to NEMA-NU2-2007 protocol, and compared to that for (18)F. The method was applied to a patient study following radioembolization to estimate actual implanted radioactivity.Increasing the number of OSEM iterations visually deteriorated image data and resulted in a larger overall difference of hot concentration measures when considering both count high and count poor data. The average difference between measured and true total activity and background concentration was found to be +5% and +5%, respectively. Measured hot-sphere concentration was linear across all datasets, and while estimated to be within error of expected values, was consistently underestimated by an average of 23%, 12%, and 8%, when using a CT-derived, 50% threshold-derived, and 70% threshold-derived volume of interest, respectively. Partial volume effects were evident in all but the largest sphere, following an expected relationship between object size and recovery coefficient, inferior to that of (18)F. Time-of-flight improved contrast of hot-spheres but resulted in a deterioration of background variability, following a similar trend to that seen with (18)F. The patient data estimated a total implanted activity of 1643 MBq, compared to the intended dose of 1780 MBq, with a difference most likely due to residual and error in the initial dose calibration.Quantitative (90)Y PET with a state-of-the-art PET∕CT scanner with time-of-flight and standard corrections for photon interactions demonstrates consistent and acceptable measures of total activity and radionuclide concentration across a range of realistic count statistics. The method is suitable for measuring the radioactivity delivered at the time of (90)Y therapy with the potential for absorbed dose calculation." @default.
• W2072783248 created "2016-06-24" @default.
• W2072783248 creator A5001916793 @default.
• W2072783248 creator A5010655665 @default.
• W2072783248 creator A5017851983 @default.
• W2072783248 creator A5023642166 @default.
• W2072783248 creator A5083131273 @default.
• W2072783248 date "2012-11-01" @default.
• W2072783248 modified "2023-09-26" @default.
• W2072783248 title "Quantitative ⁹⁰ Y image reconstruction in PET" @default.
• W2072783248 cites W1987139293 @default.
• W2072783248 cites W2002125370 @default.
• W2072783248 cites W2009537524 @default.
• W2072783248 cites W2013904762 @default.
• W2072783248 cites W2016601954 @default.
• W2072783248 cites W2156781004 @default.
• W2072783248 cites W2163610344 @default.
• W2072783248 doi "https://doi.org/10.1118/1.4762403" @default.
• W2072783248 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23127106" @default.
• W2072783248 hasPublicationYear "2012" @default.
• W2072783248 type Work @default.
• W2072783248 sameAs 2072783248 @default.
• W2072783248 citedByCount "53" @default.
• W2072783248 countsByYear W20727832482013 @default.
• W2072783248 countsByYear W20727832482014 @default.
• W2072783248 countsByYear W20727832482015 @default.
• W2072783248 countsByYear W20727832482016 @default.
• W2072783248 countsByYear W20727832482017 @default.
• W2072783248 countsByYear W20727832482018 @default.
• W2072783248 countsByYear W20727832482019 @default.
• W2072783248 countsByYear W20727832482020 @default.
• W2072783248 countsByYear W20727832482021 @default.
• W2072783248 countsByYear W20727832482022 @default.
• W2072783248 crossrefType "journal-article" @default.
• W2072783248 hasAuthorship W2072783248A5001916793 @default.
• W2072783248 hasAuthorship W2072783248A5010655665 @default.
• W2072783248 hasAuthorship W2072783248A5017851983 @default.
• W2072783248 hasAuthorship W2072783248A5023642166 @default.
• W2072783248 hasAuthorship W2072783248A5083131273 @default.
• W2072783248 hasConcept C104293457 @default.
• W2072783248 hasConcept C121332964 @default.
• W2072783248 hasConcept C136229726 @default.
• W2072783248 hasConcept C141379421 @default.
• W2072783248 hasConcept C154945302 @default.
• W2072783248 hasConcept C192562407 @default.
• W2072783248 hasConcept C2775842073 @default.
• W2072783248 hasConcept C2989005 @default.
• W2072783248 hasConcept C31601959 @default.
• W2072783248 hasConcept C33923547 @default.
• W2072783248 hasConcept C41008148 @default.
• W2072783248 hasConcept C71924100 @default.
• W2072783248 hasConcept C82233179 @default.
• W2072783248 hasConceptScore W2072783248C104293457 @default.
• W2072783248 hasConceptScore W2072783248C121332964 @default.
• W2072783248 hasConceptScore W2072783248C136229726 @default.
• W2072783248 hasConceptScore W2072783248C141379421 @default.
• W2072783248 hasConceptScore W2072783248C154945302 @default.
• W2072783248 hasConceptScore W2072783248C192562407 @default.
• W2072783248 hasConceptScore W2072783248C2775842073 @default.
• W2072783248 hasConceptScore W2072783248C2989005 @default.
• W2072783248 hasConceptScore W2072783248C31601959 @default.
• W2072783248 hasConceptScore W2072783248C33923547 @default.
• W2072783248 hasConceptScore W2072783248C41008148 @default.
• W2072783248 hasConceptScore W2072783248C71924100 @default.
• W2072783248 hasConceptScore W2072783248C82233179 @default.
• W2072783248 hasIssue "11" @default.
• W2072783248 hasLocation W20727832481 @default.
• W2072783248 hasLocation W20727832482 @default.
• W2072783248 hasOpenAccess W2072783248 @default.
• W2072783248 hasPrimaryLocation W20727832481 @default.
• W2072783248 hasRelatedWork W1969496878 @default.
• W2072783248 hasRelatedWork W1991553034 @default.
• W2072783248 hasRelatedWork W2036177004 @default.
• W2072783248 hasRelatedWork W2080848024 @default.
• W2072783248 hasRelatedWork W2086625808 @default.
• W2072783248 hasRelatedWork W2105162923 @default.
• W2072783248 hasRelatedWork W2215132873 @default.
• W2072783248 hasRelatedWork W2234282832 @default.
• W2072783248 hasRelatedWork W2310453852 @default.
• W2072783248 hasRelatedWork W2467305766 @default.
• W2072783248 hasVolume "39" @default.
• W2072783248 isParatext "false" @default.
• W2072783248 isRetracted "false" @default.
• W2072783248 magId "2072783248" @default.
• W2072783248 workType "article" @default.