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- W2072812341 abstract "4,5-Bis(1,2:3,4-di-O-isopropylidene-α-d-galactopyranos-6-yl)phthalonitrile (3) was prepared by SNAr reaction of diacetone galactose 1 and 4,5-difluorophthalonitrile (2) in 96% yield. Cyclotetramerization of 3 was achieved via its isoindoline derivative 4, affording the peripherally octasubstituted galactose zinc(II) phthalocyanine 5 in 29% yield. Deprotection of 5 gave the highly water soluble octasubstituted galactose zinc(II) phthalocyanine 6 in 81% yield which will be applied as a photosensitizer in photodynamic therapy." @default.
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- W2072812341 date "2009-02-01" @default.
- W2072812341 modified "2023-09-27" @default.
- W2072812341 title "Synthesis of an octasubstituted galactose zinc(II) phthalocyanine" @default.
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- W2072812341 doi "https://doi.org/10.1016/j.tetlet.2008.12.015" @default.
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