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- W2072821752 abstract "A differential pulse polarographic method is described for detection and trace determination of benzophenone (the main impurity) in phenytoin powder. The method depends upon the polarographic activity of benzophenone in Britton-Robinson buffer pH 5.6. The limit of detection was found to be 2.5 x 10(-6) microg ml(-1). Phenytoin has been analysed polarographically after oxidation with alkaline permanganate to give benzophenone; the limit of detection was found to be 6 x 10(-6) microg ml(-1)." @default.
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- W2072821752 date "2002-05-01" @default.
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- W2072821752 title "Polarographic determination of phenytoin and benzophenone (as impurity) in pharmaceutical preparations" @default.
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- W2072821752 doi "https://doi.org/10.1016/s0731-7085(01)00669-0" @default.
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