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• W2072830412 abstract "Pain hurts — and it is often the factor that compels an individual to seek medical care. Estimates of the annual cost of health care due to pain ranges from $560 billion to $635 billion (in 2010 dollars) in the USA.1 Furthermore, chronic musculoskeletal disorders constitute a major portion of painful medical conditions.2 It is perhaps not surprising that researchers have proposed diagnosis in terms of pain mechanism, suggesting that treatment should be directed at the specific neurophysiologic mechanism at fault.3In this special issue on musculoskeletal pain, Arendt-Nielsen and Graven-Nielsen4 focus on a major hurdle in pain science: the identification of biomarkers that signal the transition from acute to chronic pain. These authors describe the nociceptive mechanisms associated with tendon, muscle, bone, and joint pain, and discuss clinical findings, including somatosensory measures, which may correlate with neuroplastic changes of nociceptive pathways. Sterling5 applies these scientific principles to the problem of whiplash associated disorder. It is well known that a significant number of those with whiplash injury will transition from an acute to a chronic pain status.6 Sterling provides evidence for prognostic factors that should be considered following motor vehicle crashes.Understanding the mechanisms at play in a musculoskeletal disorder is important particularly when it directs treatment. While manual therapies have been demonstrated to modulate pain, how do our treatment methods affect nociceptive mechanisms? de la Llave-Rincon et al.7 and Courtney et al.8 address management of musculoskeletal pain of the upper and lower quadrant, respectively, with particular emphasis on thrust and non-thrust manipulation, while Dommerholt9 discusses the use of dry needling, a treatment technique used more and more commonly by health care providers in the USA, and in particular, by physical therapists. The current issue discusses the neurobiological basis behind chronic pain and suggests that management strategies should utilize a combination of applied basic and clinical sciences. The use of manual therapies for treatment of acute and chronic pain appears promising, yet further research is needed to refine our knowledge in this important area of science." @default.
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• W2072830412 date "2011-11-01" @default.
• W2072830412 modified "2023-10-17" @default.
• W2072830412 title "Identifying the cut-point: the transition from acute to chronic musculoskeletal pain" @default.
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• W2072830412 doi "https://doi.org/10.1179/106698111x13129729551868" @default.
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