Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072870070> ?p ?o ?g. }
- W2072870070 endingPage "8" @default.
- W2072870070 startingPage "1" @default.
- W2072870070 abstract "Antral follicular growth in the ovary is characterized by rapid expansion of granulosa cells accompanied by a rising complexity of their functionality. Within two weeks the number of human granulosa cells increases from less than 500,000 to more than 50 millions cells per follicle and differentiates into groups of cells with a variety of specialized functions involved in steroidogenesis, nursing the oocyte, and forming a functional syncitium. Both the rapid proliferation and different specialized functions of the granulosa cells can only be explained through the involvement of stem cells. However, luteinizing granulosa cells were believed to be terminally differentiated cells. Only recently, stem and progenitor cells with FSH-receptor activity were identified in populations of luteinizing granulosa cells obtained during oocyte collected for assisted reproduction. In the presence of the leukaemia-inhibiting factor (LIF), it was possible to culture a subpopulation of the luteinizing granulosa cells over prolonged time periods. Furthermore, when embedded in a matrix consisting of collagen type I, these cells continued to express the FSH receptor over prolonged time periods, developed globular formations that surrogated as follicle-like structures, providing a promising tool for reproductive biology." @default.
- W2072870070 created "2016-06-24" @default.
- W2072870070 creator A5043355162 @default.
- W2072870070 creator A5046492899 @default.
- W2072870070 date "2013-01-01" @default.
- W2072870070 modified "2023-09-27" @default.
- W2072870070 title "Cells with Stem Cell Characteristics in Somatic Compartments of the Ovary" @default.
- W2072870070 cites W1653876269 @default.
- W2072870070 cites W1708429683 @default.
- W2072870070 cites W1785864042 @default.
- W2072870070 cites W1963528166 @default.
- W2072870070 cites W1964968486 @default.
- W2072870070 cites W1965369911 @default.
- W2072870070 cites W1977135603 @default.
- W2072870070 cites W1984437024 @default.
- W2072870070 cites W1985122025 @default.
- W2072870070 cites W1986598723 @default.
- W2072870070 cites W1990835088 @default.
- W2072870070 cites W1997842732 @default.
- W2072870070 cites W2003792361 @default.
- W2072870070 cites W2006192685 @default.
- W2072870070 cites W2014639797 @default.
- W2072870070 cites W2017666826 @default.
- W2072870070 cites W2024084340 @default.
- W2072870070 cites W2029231027 @default.
- W2072870070 cites W2030873226 @default.
- W2072870070 cites W2031721014 @default.
- W2072870070 cites W2031954824 @default.
- W2072870070 cites W2037965606 @default.
- W2072870070 cites W2039079134 @default.
- W2072870070 cites W2039550497 @default.
- W2072870070 cites W2040132375 @default.
- W2072870070 cites W2040536784 @default.
- W2072870070 cites W2042272294 @default.
- W2072870070 cites W2046360871 @default.
- W2072870070 cites W2047247552 @default.
- W2072870070 cites W2048120373 @default.
- W2072870070 cites W2048876252 @default.
- W2072870070 cites W2048989707 @default.
- W2072870070 cites W2050323749 @default.
- W2072870070 cites W2053347930 @default.
- W2072870070 cites W2054325204 @default.
- W2072870070 cites W2054886233 @default.
- W2072870070 cites W2055162669 @default.
- W2072870070 cites W2056045995 @default.
- W2072870070 cites W2057836896 @default.
- W2072870070 cites W2059921402 @default.
- W2072870070 cites W2060926602 @default.
- W2072870070 cites W2062953809 @default.
- W2072870070 cites W2067970235 @default.
- W2072870070 cites W2081104479 @default.
- W2072870070 cites W2082298043 @default.
- W2072870070 cites W2088780763 @default.
- W2072870070 cites W2089206964 @default.
- W2072870070 cites W2091002895 @default.
- W2072870070 cites W2105688914 @default.
- W2072870070 cites W2114088513 @default.
- W2072870070 cites W2118946046 @default.
- W2072870070 cites W2122685595 @default.
- W2072870070 cites W2122713961 @default.
- W2072870070 cites W2122851311 @default.
- W2072870070 cites W2127659252 @default.
- W2072870070 cites W2128050737 @default.
- W2072870070 cites W2128654723 @default.
- W2072870070 cites W2129287962 @default.
- W2072870070 cites W2133200515 @default.
- W2072870070 cites W2133344686 @default.
- W2072870070 cites W2138165502 @default.
- W2072870070 cites W2144108148 @default.
- W2072870070 cites W2148459495 @default.
- W2072870070 cites W2161105368 @default.
- W2072870070 cites W2166919456 @default.
- W2072870070 cites W2271900218 @default.
- W2072870070 cites W2274559801 @default.
- W2072870070 cites W2400376175 @default.
- W2072870070 cites W4231814308 @default.
- W2072870070 cites W4239563963 @default.
- W2072870070 cites W4242869804 @default.
- W2072870070 cites W4244435500 @default.
- W2072870070 cites W4244622279 @default.
- W2072870070 cites W4248985202 @default.
- W2072870070 cites W4251577583 @default.
- W2072870070 cites W98321690 @default.
- W2072870070 doi "https://doi.org/10.1155/2013/310859" @default.
- W2072870070 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3591217" @default.
- W2072870070 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23484108" @default.
- W2072870070 hasPublicationYear "2013" @default.
- W2072870070 type Work @default.
- W2072870070 sameAs 2072870070 @default.
- W2072870070 citedByCount "29" @default.
- W2072870070 countsByYear W20728700702014 @default.
- W2072870070 countsByYear W20728700702015 @default.
- W2072870070 countsByYear W20728700702016 @default.
- W2072870070 countsByYear W20728700702018 @default.
- W2072870070 countsByYear W20728700702019 @default.
- W2072870070 countsByYear W20728700702020 @default.
- W2072870070 countsByYear W20728700702021 @default.
- W2072870070 countsByYear W20728700702022 @default.