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• W2072906760 abstract "The goal of the present study was to provide a comprehensive and quantitative description of neurons immunoreactive for γ-aminobutyric acid (GABA) in the inferior colliculus (IC) of the cat. Neurons were investigated with two different antisera and two different incubation methods. Free-floating frozen or vibratome-cut sections were incubated either with an antiserum to glutamic acid decarboxylase (GAD) or to GABA conjugated to protein with glutaraldehyde. Additional 1.5-μm-thick sections were incubated with the GABA antiserum after embedding and removal of the plastic. Quantitative data were obtained from much of this material. Despite the use of these different antisera and reaction methods, the results obtained were remarkably similar. The results show that GAD- or GABA-positive neurons represent a significant population of cells in the central nucleus of the IC, up to 20% of the neurons. Most of these neurons have large or medium-sized perikarya. In contrast, immunonegative neurons are medium-sized or small. Many GABA-positive neurons had proximal dendrites or somata oriented in parallel to the fibrodendritic laminae of the central nucleus and are presumed to be disc-shaped neurons. Others have an orthogonal orientation and are presumed to be stellate cells. Large GABA-positive neurons form two groups, those with many axosomatic endings and those with few. Collectively, these observations suggest that there are several types of GABAergic neuron in the central nucleus and, by extension, that these may participate in many types of inhibitory circuits. © Wiley-Liss, Inc." @default.
• W2072906760 created "2016-06-24" @default.
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• W2072906760 date "1994-02-01" @default.
• W2072906760 modified "2023-10-18" @default.
• W2072906760 title "Morphology of GABAergic neurons in the inferior colliculus of the cat" @default.
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• W2072906760 doi "https://doi.org/10.1002/cne.903400104" @default.
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