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- W2072911208 abstract "For more than 50 years the quantity absorbed dose has been the basic physical quantity in the medical applications of ionising radiation as well as radiological protection against harm from ionising radiation. In radiotherapy relatively high doses are applied (to a part of the human body) within a short period and the absorbed dose is mainly correlated with deterministic effects such as cell killing and tissue damage. In contrast, in radiological protection one is dealing with low doses and low dose rates and long-term stochastic effects in tissue such as cancer induction. The dose quantity (absorbed dose) is considered to be correlated with the probability of cancer incidence and thus risk induced by exposure. ICRP has developed specific dosimetric quantities for radiological protection that allow the extent of exposure to ionising radiation from whole and partial body external radiation as well as from intakes of radionuclides to be taken into account by one quantity. Moreover, radiological protection quantities are designed to provide a correlation with risk of radiation induced cancer. In addition, operational dose quantities have been defined for use in measurements of external radiation exposure and practical applications. The paper describes the concept and considerations underlying the actual system of dose quantities, and discusses the advantage as well as the limitations of applicability of such a system. For example, absorbed dose is a non-stochastic quantity defined at any point in matter. All dose quantities in use are based on an averaging procedure. Stochastic effects and microscopic biological and energy deposition structures are not considered in the definition. Absorbed dose is correlated to the initial very short phase of the radiation interaction with tissue while the radiation induced biological reactions of the tissue may last for minutes or hours or even longer. There are many parameters other than absorbed dose that influence the process of cancer induction, which may influence the consideration of cells and/or tissues at risk which are most important for radiological protection." @default.
- W2072911208 created "2016-06-24" @default.
- W2072911208 creator A5059986197 @default.
- W2072911208 date "2004-12-15" @default.
- W2072911208 modified "2023-10-16" @default.
- W2072911208 title "Dose quantities in radiation protection and their limitations" @default.
- W2072911208 doi "https://doi.org/10.1093/rpd/nch097" @default.
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