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- W2072912010 abstract "We examined the effects of agents/conditions that raise intracellular cAMP concentration in the induction of the 47,000-dalton RI cAMP-binding protein in the neurite-minus N1A-103 mouse neuroblastoma cells. The amount of RI in cell extracts was quantitated by photoaffinity labeling with 8-N3-[32P]cAMP and by ELISA and Western blot. Our results showed that treatment of the N1A-103 neuroblastoma cells with 20 microM forskolin or 1 mM dibutyryl cAMP, or reducing the serum concentration in the culture medium from 10% to 1% caused a 3-4 fold increase in the amount of RJ. Our results suggest that the induction of RJ can occur independent of morphological differentiation in the mouse neuroblastoma cells." @default.
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- W2072912010 date "1987-10-01" @default.
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- W2072912010 title "Induction of the RI cAMP-binding protein in the “neurite-minus” N1A-103 mouse neuroblastoma cell line" @default.
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- W2072912010 doi "https://doi.org/10.1016/0006-291x(87)91117-x" @default.
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