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- W2072949667 abstract "Nerve growth factor (NGF) is known to induce differentiation of pheochromocytoma into sympathetic neuron-like cells. Tetrahydrobiopterin (BPH4) and total biopterin (BP) levels in PC12h, a subclonal line of PC12, were transiently increased by NGF: the increase in BPH4 and BP reached the maximum (20-25 ng/mg protein = about 2-fold over the control level) at 24 h after the treatment was started. After 2-3 days, the BPH4 and BP levels decreased to the same level as in control cells. The NGF concentration which gave a half maximal BP increase by 24 h-treatment was around 1 ng/ml." @default.
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- W2072949667 date "1988-05-01" @default.
- W2072949667 modified "2023-09-23" @default.
- W2072949667 title "Nerve growth factor transiently increases tetrahydrobiopterin and total biopterin contents of pheochromocytoma PCl2h cells" @default.
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- W2072949667 doi "https://doi.org/10.1016/s0006-291x(88)81235-x" @default.
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