FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072960914> ?p ?o ?g. }

• W2072960914 endingPage "389" @default.
• W2072960914 startingPage "381" @default.
• W2072960914 abstract "In humans, great apes, and different monkey species, the major histocompatibility complex (MHC) class II DRB region is known to display considerable copy number variation. The microsatellite D6S2878 has been shown to be a valuable marker for haplotyping the DR region in humans and macaque species. The present report illustrates that chimpanzee haplotypes also can be discriminated with this marker. The analyses resulted in the description of nine different region configurations, of which seven are present within the West African chimpanzee population studied. The region configurations vary in gene content from two up to five DRB genes. Subsequent cDNA sequencing increased the number of known full-length Patr-DRB sequences from 3 to 32, and shows that one to three Patr-DRB genes per haplotype apparently produce functional transcripts. This is more or less comparable to humans and rhesus macaques. Moreover, microsatellite analysis in concert with full-length DRB gene sequencing showed that the Patr-DRB*W9 and -DRB3*01/02 lineages most likely arose from a common ancestral lineage: hence, the Patr-DRB*W9 lineage was renamed to Patr-DRB3*07. Overall, the data demonstrate that the D6S2878 microsatellite marker allows fast and accurate haplotyping of the Patr-DRB region. In addition, the limited amount of allelic variation observed at the various Patr-DRB genes is in agreement with the fact that chimpanzees experienced a selective sweep that may have been caused by an ancient retroviral infection." @default.
• W2072960914 created "2016-06-24" @default.
• W2072960914 creator A5010234448 @default.
• W2072960914 creator A5010537554 @default.
• W2072960914 creator A5036545558 @default.
• W2072960914 creator A5048291430 @default.
• W2072960914 creator A5052566235 @default.
• W2072960914 creator A5057315343 @default.
• W2072960914 date "2009-12-01" @default.
• W2072960914 modified "2023-09-27" @default.
• W2072960914 title "The chimpanzee Mhc-DRB region revisited: Gene content, polymorphism, pseudogenes, and transcripts" @default.
• W2072960914 cites W1488823075 @default.
• W2072960914 cites W1506969536 @default.
• W2072960914 cites W1563485932 @default.
• W2072960914 cites W1575311801 @default.
• W2072960914 cites W1809282779 @default.
• W2072960914 cites W1847394961 @default.
• W2072960914 cites W1969632872 @default.
• W2072960914 cites W1981470925 @default.
• W2072960914 cites W1982726965 @default.
• W2072960914 cites W1986160833 @default.
• W2072960914 cites W1987829549 @default.
• W2072960914 cites W1990879527 @default.
• W2072960914 cites W2000131964 @default.
• W2072960914 cites W2006732227 @default.
• W2072960914 cites W2013024562 @default.
• W2072960914 cites W2019613481 @default.
• W2072960914 cites W2040829499 @default.
• W2072960914 cites W2041842205 @default.
• W2072960914 cites W2046202438 @default.
• W2072960914 cites W2050774485 @default.
• W2072960914 cites W2051044641 @default.
• W2072960914 cites W2051799841 @default.
• W2072960914 cites W2052187293 @default.
• W2072960914 cites W2052357793 @default.
• W2072960914 cites W2061891804 @default.
• W2072960914 cites W2064890497 @default.
• W2072960914 cites W2066212292 @default.
• W2072960914 cites W2067007779 @default.
• W2072960914 cites W2067200416 @default.
• W2072960914 cites W2074095020 @default.
• W2072960914 cites W2076225720 @default.
• W2072960914 cites W2078895073 @default.
• W2072960914 cites W2087580620 @default.
• W2072960914 cites W2104789942 @default.
• W2072960914 cites W2109576844 @default.
• W2072960914 cites W2113745656 @default.
• W2072960914 cites W2115392836 @default.
• W2072960914 cites W2122310307 @default.
• W2072960914 cites W2127901973 @default.
• W2072960914 cites W2130141655 @default.
• W2072960914 cites W2136883672 @default.
• W2072960914 cites W2137545654 @default.
• W2072960914 cites W2152147412 @default.
• W2072960914 cites W2152778706 @default.
• W2072960914 cites W28108870 @default.
• W2072960914 cites W4230123290 @default.
• W2072960914 doi "https://doi.org/10.1016/j.molimm.2009.09.003" @default.
• W2072960914 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2788069" @default.
• W2072960914 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19800692" @default.
• W2072960914 hasPublicationYear "2009" @default.
• W2072960914 type Work @default.
• W2072960914 sameAs 2072960914 @default.
• W2072960914 citedByCount "23" @default.
• W2072960914 countsByYear W20729609142012 @default.
• W2072960914 countsByYear W20729609142013 @default.
• W2072960914 countsByYear W20729609142014 @default.
• W2072960914 countsByYear W20729609142015 @default.
• W2072960914 countsByYear W20729609142016 @default.
• W2072960914 countsByYear W20729609142017 @default.
• W2072960914 countsByYear W20729609142018 @default.
• W2072960914 countsByYear W20729609142020 @default.
• W2072960914 crossrefType "journal-article" @default.
• W2072960914 hasAuthorship W2072960914A5010234448 @default.
• W2072960914 hasAuthorship W2072960914A5010537554 @default.
• W2072960914 hasAuthorship W2072960914A5036545558 @default.
• W2072960914 hasAuthorship W2072960914A5048291430 @default.
• W2072960914 hasAuthorship W2072960914A5052566235 @default.
• W2072960914 hasAuthorship W2072960914A5057315343 @default.
• W2072960914 hasBestOaLocation W20729609142 @default.
• W2072960914 hasConcept C104317684 @default.
• W2072960914 hasConcept C141231307 @default.
• W2072960914 hasConcept C144024400 @default.
• W2072960914 hasConcept C149923435 @default.
• W2072960914 hasConcept C151730666 @default.
• W2072960914 hasConcept C180754005 @default.
• W2072960914 hasConcept C197754878 @default.
• W2072960914 hasConcept C207936829 @default.
• W2072960914 hasConcept C2776817793 @default.
• W2072960914 hasConcept C2778950215 @default.
• W2072960914 hasConcept C2779175743 @default.
• W2072960914 hasConcept C2908647359 @default.
• W2072960914 hasConcept C34957205 @default.
• W2072960914 hasConcept C54355233 @default.
• W2072960914 hasConcept C61320498 @default.
• W2072960914 hasConcept C78458016 @default.
• W2072960914 hasConcept C86803240 @default.
• W2072960914 hasConceptScore W2072960914C104317684 @default.

• next