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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2072993811> ?p ?o ?g. }

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• W2072993811 abstract "A new series of 4-aryl-4H-chromenes bearing a 5-arylisoxazol-3-yl moiety at the C-4 position were prepared as potential anticancer agents. The in vitro cytotoxic activity of the synthesized compounds was investigated against a panel of tumor cell lines including MCF-7 (breast cancer), KB (nasopharyngeal epidermoid carcinoma), Hep-G2 (liver carcinoma), MDA-MB-231 (breast cancer), and SKNMC (human neuroblastoma) using the MTT colorimetric assay. Doxorubicin, a well-known anticancer drug, was used as positive standard drug. Among the synthesized compounds, the 5-(3-methylphenyl)isoxazol-3-yl analog (7j) showed the most potent cytotoxic activity against all five human tumor cell lines." @default.
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• W2072993811 date "2012-01-20" @default.
• W2072993811 modified "2023-09-27" @default.
• W2072993811 title "2-Amino-3-cyano-4-(5-arylisoxazol-3-yl)-4H-chromenes: Synthesis and In Vitro Cytotoxic Activity" @default.
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• W2072993811 doi "https://doi.org/10.1002/ardp.201100345" @default.
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