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- W2073005087 abstract "Novel surface plasmon resonance (SPR) biosensors based on Au-graphene (Au-Gra) nanohybrids and Ag-graphene (Ag-Gra) nanohybrids for the detection of mouse IgG were developed. The biosensors proposed are label free, and have high sensitivity and selectivity for biosensing. Au-Gra and Ag-Gra nanohybrids were synthesized in a simple, effective and rapid way, and further characterized by X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM) and UV–vis absorption spectroscopy. These nanohybrids were assembled on the Au film through 1,6-hexanedithiol by covalent attachment. And the antibody was bound to the nanohybrids through 3-mercaptopropinic acid. Some experimental conditions were determined and optimized. In the optimal conditions, the biosensors based on Au-Gra nanohybrids and Ag-Gra nanohybrids show a good response to mouse IgG in the concentration range of 0.30–40.00 μg mL−1 and 0.15–40.00 μg mL−1, respectively. While, the biosensor unmodified with nanohybrids shows a response to mouse IgG in the concentration range of 2.50–40.00 μg mL−1. As a result, the performance of the biosensor based on metal nanoparticles decorated with graphene has been improved significantly." @default.
- W2073005087 created "2016-06-24" @default.
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- W2073005087 date "2013-11-01" @default.
- W2073005087 modified "2023-10-17" @default.
- W2073005087 title "Novel SPR biosensors based on metal nanoparticles decorated with graphene for immunoassay" @default.
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- W2073005087 doi "https://doi.org/10.1016/j.snb.2013.07.055" @default.
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