FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073018148> ?p ?o ?g. }

• W2073018148 endingPage "e80576" @default.
• W2073018148 startingPage "e80576" @default.
• W2073018148 abstract "Evaluation of (18)F-FDG uptake value via PET is central to current methods of diagnosis and staging of non-small cell lung cancer (NSCLC) due to its ability to evaluate expression levels of key regulators associated with glucose metabolism in tumor cells. Tp53-induced glycolysis and apoptosis regulator (TIGAR) is an important P53-induced protein that can inhibit glycolysis; however, there have been few clinical studies on its mechanism. Here we have investigated the relationship between TIGAR expression and (18)F-FDG PET in tumors, along with its relationship with the clinical characteristics of NSCLC.We analyzed SUVmax in 79 patients with NSCLC through immunohistochemical staining of TIGAR and five other biological markers associated with tumor cell glycolysis, in order to evaluate the correlation between their expression and SUVmax. We also plotted Kaplan-Meier survival curves to assess TIGAR expression with the prognosis and survival of patients with NSCLC.The key findings were as follows: SUVmax was negatively correlated with the expression of TIGAR (r = -0.31, p<0.01); TIGAR expression was correlated with tumor size (p = 0.01), histological type (p<0.01), differentiation degree (p<0.01) and lymph node metastasis(p<0.01) in patients with NSCLC; and the survival time of patients whose TIGAR was negatively expressed was significantly shorter than for those whose TIGAR was positively expressed (P = 0.023).The expression of TIGAR in primary tumors is significantly correlated with SUVmax, and low expression of TIGAR may predict a worse clinical outcome in patients with NSCLC." @default.
• W2073018148 created "2016-06-24" @default.
• W2073018148 creator A5001556982 @default.
• W2073018148 creator A5014942240 @default.
• W2073018148 creator A5018617993 @default.
• W2073018148 creator A5033547724 @default.
• W2073018148 creator A5056854347 @default.
• W2073018148 creator A5061972961 @default.
• W2073018148 creator A5067298527 @default.
• W2073018148 creator A5073501391 @default.
• W2073018148 date "2013-12-10" @default.
• W2073018148 modified "2023-10-17" @default.
• W2073018148 title "TIGAR Is Correlated with Maximal Standardized Uptake Value on FDG-PET and Survival in Non-Small Cell Lung Cancer" @default.
• W2073018148 cites W1511697598 @default.
• W2073018148 cites W1979087114 @default.
• W2073018148 cites W1986642666 @default.
• W2073018148 cites W1995140801 @default.
• W2073018148 cites W2000617713 @default.
• W2073018148 cites W2001633284 @default.
• W2073018148 cites W2019429039 @default.
• W2073018148 cites W2024684558 @default.
• W2073018148 cites W2028897202 @default.
• W2073018148 cites W2030992905 @default.
• W2073018148 cites W2034042949 @default.
• W2073018148 cites W2053762753 @default.
• W2073018148 cites W2060380495 @default.
• W2073018148 cites W2089245306 @default.
• W2073018148 cites W2092506655 @default.
• W2073018148 cites W2094440255 @default.
• W2073018148 cites W2098234787 @default.
• W2073018148 cites W2117692326 @default.
• W2073018148 cites W2119239003 @default.
• W2073018148 cites W2120976938 @default.
• W2073018148 cites W2158665241 @default.
• W2073018148 cites W2170441875 @default.
• W2073018148 doi "https://doi.org/10.1371/journal.pone.0080576" @default.
• W2073018148 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3868468" @default.
• W2073018148 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24363807" @default.
• W2073018148 hasPublicationYear "2013" @default.
• W2073018148 type Work @default.
• W2073018148 sameAs 2073018148 @default.
• W2073018148 citedByCount "18" @default.
• W2073018148 countsByYear W20730181482016 @default.
• W2073018148 countsByYear W20730181482017 @default.
• W2073018148 countsByYear W20730181482018 @default.
• W2073018148 countsByYear W20730181482019 @default.
• W2073018148 countsByYear W20730181482020 @default.
• W2073018148 countsByYear W20730181482021 @default.
• W2073018148 countsByYear W20730181482022 @default.
• W2073018148 countsByYear W20730181482023 @default.
• W2073018148 crossrefType "journal-article" @default.
• W2073018148 hasAuthorship W2073018148A5001556982 @default.
• W2073018148 hasAuthorship W2073018148A5014942240 @default.
• W2073018148 hasAuthorship W2073018148A5018617993 @default.
• W2073018148 hasAuthorship W2073018148A5033547724 @default.
• W2073018148 hasAuthorship W2073018148A5056854347 @default.
• W2073018148 hasAuthorship W2073018148A5061972961 @default.
• W2073018148 hasAuthorship W2073018148A5067298527 @default.
• W2073018148 hasAuthorship W2073018148A5073501391 @default.
• W2073018148 hasBestOaLocation W20730181481 @default.
• W2073018148 hasConcept C121608353 @default.
• W2073018148 hasConcept C126322002 @default.
• W2073018148 hasConcept C142724271 @default.
• W2073018148 hasConcept C143998085 @default.
• W2073018148 hasConcept C190283241 @default.
• W2073018148 hasConcept C199374082 @default.
• W2073018148 hasConcept C20251656 @default.
• W2073018148 hasConcept C204232928 @default.
• W2073018148 hasConcept C2775842073 @default.
• W2073018148 hasConcept C2776256026 @default.
• W2073018148 hasConcept C2777714996 @default.
• W2073018148 hasConcept C2779013556 @default.
• W2073018148 hasConcept C2780849966 @default.
• W2073018148 hasConcept C2989005 @default.
• W2073018148 hasConcept C502942594 @default.
• W2073018148 hasConcept C55493867 @default.
• W2073018148 hasConcept C62231903 @default.
• W2073018148 hasConcept C71924100 @default.
• W2073018148 hasConcept C86803240 @default.
• W2073018148 hasConceptScore W2073018148C121608353 @default.
• W2073018148 hasConceptScore W2073018148C126322002 @default.
• W2073018148 hasConceptScore W2073018148C142724271 @default.
• W2073018148 hasConceptScore W2073018148C143998085 @default.
• W2073018148 hasConceptScore W2073018148C190283241 @default.
• W2073018148 hasConceptScore W2073018148C199374082 @default.
• W2073018148 hasConceptScore W2073018148C20251656 @default.
• W2073018148 hasConceptScore W2073018148C204232928 @default.
• W2073018148 hasConceptScore W2073018148C2775842073 @default.
• W2073018148 hasConceptScore W2073018148C2776256026 @default.
• W2073018148 hasConceptScore W2073018148C2777714996 @default.
• W2073018148 hasConceptScore W2073018148C2779013556 @default.
• W2073018148 hasConceptScore W2073018148C2780849966 @default.
• W2073018148 hasConceptScore W2073018148C2989005 @default.
• W2073018148 hasConceptScore W2073018148C502942594 @default.
• W2073018148 hasConceptScore W2073018148C55493867 @default.
• W2073018148 hasConceptScore W2073018148C62231903 @default.
• W2073018148 hasConceptScore W2073018148C71924100 @default.
• W2073018148 hasConceptScore W2073018148C86803240 @default.

• next