FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073030392> ?p ?o ?g. }

• W2073030392 endingPage "1379" @default.
• W2073030392 startingPage "1368" @default.
• W2073030392 abstract "Dynamic positron emission tomography (PET) data are usually quantified using compartment models (CMs) or derived graphical approaches. Often, however, CMs either do not properly describe the tracer kinetics, or are not identifiable, leading to nonphysiologic estimates of the tracer binding. The PET data are modeled as the convolution of the metabolite-corrected input function and the tracer impulse response function (IRF) in the tissue. Using nonparametric deconvolution methods, it is possible to obtain model-free estimates of the IRF, from which functionals related to tracer volume of distribution and binding may be computed, but this approach has rarely been applied in PET. Here, we apply nonparametric deconvolution using singular value decomposition to simulated and test–retest clinical PET data with four reversible tracers well characterized by CMs ([ 11 C]CUMI-101, [ 11 C]DASB, [ 11 C]PE2I, and [ 11 C]WAY-100635), and systematically compare reproducibility, reliability, and identifiability of various IRF-derived functionals with that of traditional CMs outcomes. Results show that nonparametric deconvolution, completely free of any model assumptions, allows for estimates of tracer volume of distribution and binding that are very close to the estimates obtained with CMs and, in some cases, show better test–retest performance than CMs outcomes." @default.
• W2073030392 created "2016-06-24" @default.
• W2073030392 creator A5023581810 @default.
• W2073030392 creator A5034108863 @default.
• W2073030392 creator A5081965846 @default.
• W2073030392 date "2015-04-15" @default.
• W2073030392 modified "2023-10-02" @default.
• W2073030392 title "Model-Free Quantification of Dynamic PET Data Using Nonparametric Deconvolution" @default.
• W2073030392 cites W1944705852 @default.
• W2073030392 cites W1976787795 @default.
• W2073030392 cites W1989018222 @default.
• W2073030392 cites W1992355633 @default.
• W2073030392 cites W1995875735 @default.
• W2073030392 cites W1996644227 @default.
• W2073030392 cites W1996692478 @default.
• W2073030392 cites W1996925582 @default.
• W2073030392 cites W2014577202 @default.
• W2073030392 cites W2017367842 @default.
• W2073030392 cites W2021065610 @default.
• W2073030392 cites W2034946706 @default.
• W2073030392 cites W2035837210 @default.
• W2073030392 cites W2042464027 @default.
• W2073030392 cites W2047232697 @default.
• W2073030392 cites W2047423950 @default.
• W2073030392 cites W2058747520 @default.
• W2073030392 cites W2071881327 @default.
• W2073030392 cites W2073879852 @default.
• W2073030392 cites W2094339250 @default.
• W2073030392 cites W2107395405 @default.
• W2073030392 cites W2108164203 @default.
• W2073030392 cites W2112278807 @default.
• W2073030392 cites W2112492808 @default.
• W2073030392 cites W2116517414 @default.
• W2073030392 cites W2117523434 @default.
• W2073030392 cites W2126050692 @default.
• W2073030392 cites W2128040155 @default.
• W2073030392 cites W2134978734 @default.
• W2073030392 cites W2139351430 @default.
• W2073030392 cites W2144761146 @default.
• W2073030392 cites W2148726987 @default.
• W2073030392 cites W2154625249 @default.
• W2073030392 cites W2157589417 @default.
• W2073030392 cites W2172329526 @default.
• W2073030392 cites W3099329898 @default.
• W2073030392 doi "https://doi.org/10.1038/jcbfm.2015.65" @default.
• W2073030392 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4528013" @default.
• W2073030392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25873427" @default.
• W2073030392 hasPublicationYear "2015" @default.
• W2073030392 type Work @default.
• W2073030392 sameAs 2073030392 @default.
• W2073030392 citedByCount "7" @default.
• W2073030392 countsByYear W20730303922016 @default.
• W2073030392 countsByYear W20730303922018 @default.
• W2073030392 countsByYear W20730303922019 @default.
• W2073030392 countsByYear W20730303922021 @default.
• W2073030392 countsByYear W20730303922022 @default.
• W2073030392 countsByYear W20730303922023 @default.
• W2073030392 crossrefType "journal-article" @default.
• W2073030392 hasAuthorship W2073030392A5023581810 @default.
• W2073030392 hasAuthorship W2073030392A5034108863 @default.
• W2073030392 hasAuthorship W2073030392A5081965846 @default.
• W2073030392 hasBestOaLocation W20730303921 @default.
• W2073030392 hasConcept C102366305 @default.
• W2073030392 hasConcept C105795698 @default.
• W2073030392 hasConcept C11413529 @default.
• W2073030392 hasConcept C121332964 @default.
• W2073030392 hasConcept C122770356 @default.
• W2073030392 hasConcept C134306372 @default.
• W2073030392 hasConcept C154945302 @default.
• W2073030392 hasConcept C174576160 @default.
• W2073030392 hasConcept C185544564 @default.
• W2073030392 hasConcept C186060115 @default.
• W2073030392 hasConcept C2775842073 @default.
• W2073030392 hasConcept C2778863792 @default.
• W2073030392 hasConcept C2989005 @default.
• W2073030392 hasConcept C33923547 @default.
• W2073030392 hasConcept C41008148 @default.
• W2073030392 hasConcept C45347329 @default.
• W2073030392 hasConcept C50644808 @default.
• W2073030392 hasConcept C71924100 @default.
• W2073030392 hasConcept C72279823 @default.
• W2073030392 hasConcept C86803240 @default.
• W2073030392 hasConceptScore W2073030392C102366305 @default.
• W2073030392 hasConceptScore W2073030392C105795698 @default.
• W2073030392 hasConceptScore W2073030392C11413529 @default.
• W2073030392 hasConceptScore W2073030392C121332964 @default.
• W2073030392 hasConceptScore W2073030392C122770356 @default.
• W2073030392 hasConceptScore W2073030392C134306372 @default.
• W2073030392 hasConceptScore W2073030392C154945302 @default.
• W2073030392 hasConceptScore W2073030392C174576160 @default.
• W2073030392 hasConceptScore W2073030392C185544564 @default.
• W2073030392 hasConceptScore W2073030392C186060115 @default.
• W2073030392 hasConceptScore W2073030392C2775842073 @default.
• W2073030392 hasConceptScore W2073030392C2778863792 @default.
• W2073030392 hasConceptScore W2073030392C2989005 @default.
• W2073030392 hasConceptScore W2073030392C33923547 @default.
• W2073030392 hasConceptScore W2073030392C41008148 @default.
• W2073030392 hasConceptScore W2073030392C45347329 @default.

• next