Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073032752> ?p ?o ?g. }
- W2073032752 endingPage "462" @default.
- W2073032752 startingPage "456" @default.
- W2073032752 abstract "CTLA-4 is engaged on effector cells that may alter signal transduction and subsequently cytokine production. The transmission of longer repeats of (AT)(n) alleles of CTLA-4 is also associated with women undergoing recurrent miscarriage. The TNF-α known as an embryo-toxic cytokine is reported to be greater in placentas of abortion prone pregnancies.The present study investigated the role of CTLA-4+49 A/G, CTLA-4 (AT)(n) 3'UTR, TNF-α-308G/A and TNF-α-238G/A polymorphisms as a susceptibility marker for recurrent miscarriage (RM).We genotyped CTLA4+49 A/G, TNF-α-308 and TNF-α-238 gene polymorphisms in 300 patients with RM and 500 age and ethnically matched negative controls using PCR-RFLP method. While gene sequencing method was adopted for studying the CTLA-4 (AT)(n) 3'UTR polymorphism.The mutant homozygous genotype GG of CTLA4+49A/G, AA genotype and A allele of TNF-α-308, G allele of TNF-α-238 were observed to be predisposing among RM cases along with the 104 bp, 106 bp, 110 bp and 116 bp alleles of CTLA-4 (AT)(n) microsatellite repeat. GA and AG haplotypes of TNF-α were low risk associated haplotypes among recurrent miscarriage women.Roles of CTLA-4 A49G, CTLA-4 (AT)(n) 3'UTR, TNF-α-308 and TNF-α-238 polymorphisms in RM cases from North India is reflected through this study." @default.
- W2073032752 created "2016-06-24" @default.
- W2073032752 creator A5024074591 @default.
- W2073032752 creator A5041014714 @default.
- W2073032752 creator A5049692213 @default.
- W2073032752 creator A5057541473 @default.
- W2073032752 date "2012-11-01" @default.
- W2073032752 modified "2023-10-01" @default.
- W2073032752 title "Association of CTLA-4 and TNF-α polymorphism with recurrent miscarriage among North Indian women" @default.
- W2073032752 cites W1519521580 @default.
- W2073032752 cites W1921052480 @default.
- W2073032752 cites W1965223278 @default.
- W2073032752 cites W1969281049 @default.
- W2073032752 cites W1969380727 @default.
- W2073032752 cites W1976484036 @default.
- W2073032752 cites W1981492529 @default.
- W2073032752 cites W1982567339 @default.
- W2073032752 cites W1988645670 @default.
- W2073032752 cites W2013863789 @default.
- W2073032752 cites W2021277923 @default.
- W2073032752 cites W2034319984 @default.
- W2073032752 cites W2035712629 @default.
- W2073032752 cites W2045457597 @default.
- W2073032752 cites W2049032499 @default.
- W2073032752 cites W2051982093 @default.
- W2073032752 cites W2052119995 @default.
- W2073032752 cites W2065455304 @default.
- W2073032752 cites W2067301696 @default.
- W2073032752 cites W2070450646 @default.
- W2073032752 cites W2073409518 @default.
- W2073032752 cites W2075819066 @default.
- W2073032752 cites W2078735513 @default.
- W2073032752 cites W2088940433 @default.
- W2073032752 cites W2092401921 @default.
- W2073032752 cites W2099671460 @default.
- W2073032752 cites W2099694742 @default.
- W2073032752 cites W2101822729 @default.
- W2073032752 cites W2105732020 @default.
- W2073032752 cites W2121498145 @default.
- W2073032752 cites W2123705059 @default.
- W2073032752 cites W2130822830 @default.
- W2073032752 cites W2135086570 @default.
- W2073032752 cites W2149748445 @default.
- W2073032752 cites W2150916684 @default.
- W2073032752 cites W2155989955 @default.
- W2073032752 cites W2162540156 @default.
- W2073032752 cites W2167664101 @default.
- W2073032752 cites W3153504824 @default.
- W2073032752 cites W4239149238 @default.
- W2073032752 doi "https://doi.org/10.1016/j.cyto.2012.05.018" @default.
- W2073032752 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22727980" @default.
- W2073032752 hasPublicationYear "2012" @default.
- W2073032752 type Work @default.
- W2073032752 sameAs 2073032752 @default.
- W2073032752 citedByCount "39" @default.
- W2073032752 countsByYear W20730327522013 @default.
- W2073032752 countsByYear W20730327522014 @default.
- W2073032752 countsByYear W20730327522016 @default.
- W2073032752 countsByYear W20730327522017 @default.
- W2073032752 countsByYear W20730327522018 @default.
- W2073032752 countsByYear W20730327522019 @default.
- W2073032752 countsByYear W20730327522020 @default.
- W2073032752 countsByYear W20730327522021 @default.
- W2073032752 countsByYear W20730327522022 @default.
- W2073032752 countsByYear W20730327522023 @default.
- W2073032752 crossrefType "journal-article" @default.
- W2073032752 hasAuthorship W2073032752A5024074591 @default.
- W2073032752 hasAuthorship W2073032752A5041014714 @default.
- W2073032752 hasAuthorship W2073032752A5049692213 @default.
- W2073032752 hasAuthorship W2073032752A5057541473 @default.
- W2073032752 hasConcept C104317684 @default.
- W2073032752 hasConcept C135763542 @default.
- W2073032752 hasConcept C149737253 @default.
- W2073032752 hasConcept C153911025 @default.
- W2073032752 hasConcept C180754005 @default.
- W2073032752 hasConcept C197754878 @default.
- W2073032752 hasConcept C203014093 @default.
- W2073032752 hasConcept C2779234561 @default.
- W2073032752 hasConcept C2779245376 @default.
- W2073032752 hasConcept C2780625311 @default.
- W2073032752 hasConcept C31467283 @default.
- W2073032752 hasConcept C54355233 @default.
- W2073032752 hasConcept C71924100 @default.
- W2073032752 hasConcept C86803240 @default.
- W2073032752 hasConceptScore W2073032752C104317684 @default.
- W2073032752 hasConceptScore W2073032752C135763542 @default.
- W2073032752 hasConceptScore W2073032752C149737253 @default.
- W2073032752 hasConceptScore W2073032752C153911025 @default.
- W2073032752 hasConceptScore W2073032752C180754005 @default.
- W2073032752 hasConceptScore W2073032752C197754878 @default.
- W2073032752 hasConceptScore W2073032752C203014093 @default.
- W2073032752 hasConceptScore W2073032752C2779234561 @default.
- W2073032752 hasConceptScore W2073032752C2779245376 @default.
- W2073032752 hasConceptScore W2073032752C2780625311 @default.
- W2073032752 hasConceptScore W2073032752C31467283 @default.
- W2073032752 hasConceptScore W2073032752C54355233 @default.
- W2073032752 hasConceptScore W2073032752C71924100 @default.
- W2073032752 hasConceptScore W2073032752C86803240 @default.