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• W2073037269 abstract "Mesenchymal cells from the wing buds of stage 24 chick embryos undergo differentiation to cartilage when plated at high density. Treatment of these cultures with phospholipase D resulted in inhibition of chondrogenesis. Phospholipase D treatment (which produces phosphatidic acid from membrane phospholipids) was found to affect cell proliferation and to dramatically increase intracellular free calcium levels and inositol phosphate production. Intracellular free Ca2+, mobilized as a result of phosphatidylinositol phosphate hydrolysis, may therefore inhibit chondrogenesis in embryonic mesenchymal cells." @default.
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• W2073037269 date "1991-08-01" @default.
• W2073037269 modified "2023-09-26" @default.
• W2073037269 title "Inhibitory effects of phospholipase D on chondrogenesis in vitro*1" @default.
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• W2073037269 doi "https://doi.org/10.1016/0014-4827(91)90411-m" @default.
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