FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073044102> ?p ?o ?g. }

• W2073044102 endingPage "1555" @default.
• W2073044102 startingPage "1545" @default.
• W2073044102 abstract "The objective of this study was to obtain direct neurochemical measures of the central nervous system's response to a typical neuroleptic, haloperidol, in human subjects. Nine healthy volunteers participated in this study. Central nervous system neuronal activity was assessed by measuring the plasma concentration and overflow from the brain of dopamine, norepinephrine, and their lipophilic and acidic metabolites after acute intravenous administration of haloperidol. By combining bilateral internal jugular vein blood sampling with cerebral blood flow scans we were able to differentiate between cortical and subcortical responses to haloperidol. The central nervous system response to haloperidol administration displayed a degree of regional specificity. Dopamine release, estimated from the overflow of homovanillic and dihydroxyphenylacetic acids, was reduced in cortical but not subcortical brain regions. Norepinephrine turnover was increased in cortical and subcortical brain regions. The overflow of homovanillic acid from the brain into the internal jugular veins was not related quantitatively to the arterial plasma concentrations of the catecholamines examined, homovanillic and dihydroxyphenylacetic acids or prolactin. Measurements of catecholamines and their metabolites in arterial plasma gave little indication as to monoaminergic neuronal activity in the brain." @default.
• W2073044102 created "2016-06-24" @default.
• W2073044102 creator A5004760042 @default.
• W2073044102 creator A5010510721 @default.
• W2073044102 creator A5011375886 @default.
• W2073044102 creator A5028579858 @default.
• W2073044102 creator A5031436346 @default.
• W2073044102 creator A5035489509 @default.
• W2073044102 creator A5039727606 @default.
• W2073044102 creator A5082730443 @default.
• W2073044102 date "1995-03-01" @default.
• W2073044102 modified "2023-10-18" @default.
• W2073044102 title "Central nervous system noradrenergic and dopaminergic turnover in response to acute neuroleptic challenge" @default.
• W2073044102 cites W1491481957 @default.
• W2073044102 cites W1970436017 @default.
• W2073044102 cites W1973373543 @default.
• W2073044102 cites W1975461965 @default.
• W2073044102 cites W1976311853 @default.
• W2073044102 cites W1992520673 @default.
• W2073044102 cites W1998003659 @default.
• W2073044102 cites W1998040229 @default.
• W2073044102 cites W2002213732 @default.
• W2073044102 cites W2004150798 @default.
• W2073044102 cites W2011219389 @default.
• W2073044102 cites W2013718093 @default.
• W2073044102 cites W2016087155 @default.
• W2073044102 cites W2019953824 @default.
• W2073044102 cites W2022487423 @default.
• W2073044102 cites W2024924310 @default.
• W2073044102 cites W2031024794 @default.
• W2073044102 cites W2044136878 @default.
• W2073044102 cites W2045320365 @default.
• W2073044102 cites W2047474099 @default.
• W2073044102 cites W2049718785 @default.
• W2073044102 cites W2060355791 @default.
• W2073044102 cites W2061605179 @default.
• W2073044102 cites W2065199435 @default.
• W2073044102 cites W2069769057 @default.
• W2073044102 cites W2071389360 @default.
• W2073044102 cites W2072294014 @default.
• W2073044102 cites W2072435070 @default.
• W2073044102 cites W2095362394 @default.
• W2073044102 cites W2121567908 @default.
• W2073044102 cites W2137335941 @default.
• W2073044102 cites W2159996636 @default.
• W2073044102 cites W2162836351 @default.
• W2073044102 cites W2227591748 @default.
• W2073044102 cites W2413474850 @default.
• W2073044102 cites W2835846723 @default.
• W2073044102 cites W46061604 @default.
• W2073044102 doi "https://doi.org/10.1016/0024-3205(95)00120-u" @default.
• W2073044102 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7723582" @default.
• W2073044102 hasPublicationYear "1995" @default.
• W2073044102 type Work @default.
• W2073044102 sameAs 2073044102 @default.
• W2073044102 citedByCount "7" @default.
• W2073044102 countsByYear W20730441022022 @default.
• W2073044102 crossrefType "journal-article" @default.
• W2073044102 hasAuthorship W2073044102A5004760042 @default.
• W2073044102 hasAuthorship W2073044102A5010510721 @default.
• W2073044102 hasAuthorship W2073044102A5011375886 @default.
• W2073044102 hasAuthorship W2073044102A5028579858 @default.
• W2073044102 hasAuthorship W2073044102A5031436346 @default.
• W2073044102 hasAuthorship W2073044102A5035489509 @default.
• W2073044102 hasAuthorship W2073044102A5039727606 @default.
• W2073044102 hasAuthorship W2073044102A5082730443 @default.
• W2073044102 hasConcept C126322002 @default.
• W2073044102 hasConcept C134018914 @default.
• W2073044102 hasConcept C137183658 @default.
• W2073044102 hasConcept C15744967 @default.
• W2073044102 hasConcept C169760540 @default.
• W2073044102 hasConcept C170493617 @default.
• W2073044102 hasConcept C185592680 @default.
• W2073044102 hasConcept C25876315 @default.
• W2073044102 hasConcept C2775841634 @default.
• W2073044102 hasConcept C2775864247 @default.
• W2073044102 hasConcept C2778514916 @default.
• W2073044102 hasConcept C2780948584 @default.
• W2073044102 hasConcept C42219234 @default.
• W2073044102 hasConcept C42251903 @default.
• W2073044102 hasConcept C513476851 @default.
• W2073044102 hasConcept C529278444 @default.
• W2073044102 hasConcept C71924100 @default.
• W2073044102 hasConceptScore W2073044102C126322002 @default.
• W2073044102 hasConceptScore W2073044102C134018914 @default.
• W2073044102 hasConceptScore W2073044102C137183658 @default.
• W2073044102 hasConceptScore W2073044102C15744967 @default.
• W2073044102 hasConceptScore W2073044102C169760540 @default.
• W2073044102 hasConceptScore W2073044102C170493617 @default.
• W2073044102 hasConceptScore W2073044102C185592680 @default.
• W2073044102 hasConceptScore W2073044102C25876315 @default.
• W2073044102 hasConceptScore W2073044102C2775841634 @default.
• W2073044102 hasConceptScore W2073044102C2775864247 @default.
• W2073044102 hasConceptScore W2073044102C2778514916 @default.
• W2073044102 hasConceptScore W2073044102C2780948584 @default.
• W2073044102 hasConceptScore W2073044102C42219234 @default.
• W2073044102 hasConceptScore W2073044102C42251903 @default.
• W2073044102 hasConceptScore W2073044102C513476851 @default.

• next