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- W2073044265 abstract "Self-styled “evidologist” and tireless advocate of evidence based medicine. Born in Sydney, Australia, on April 7, 1966, she died of breast cancer in Sydney on Feb 1, 2009, aged 42 years. “Having a life-threatening disease is fascinating because it plunges you into a new existential world”, wrote Anna Donald some 10 months before her death. “It feels as if you've been forcefully pushed into the engine room of human existence where you start to understand, before you die, what you're made of.” Donald was not the first doctor to have written about her own disease; but few have produced prose to compare with the series of BMJ blogs in which she charted the progression of the breast cancer that killed her. Written over some 9 months, these blogs comprise a vivid insight into one exceptional woman's feelings about her impending death, and how she was coping with it. The language was sometimes humorous: “My cancer genes are being jolly selfish, in my humble view, not to mention stupid, in persisting in their kamikaze venture. If I die, so do they.” Her descriptions were often graphic, “A few days ago, my scans came back. My liver looked like a Jackson Pollock painting. Blobs, blotches, lines everywhere.” The writing was sometimes introspective and sometimes emotional, but virtually never self-pitying. Donald trained at Sydney University's medical school, but spent most of her career in the UK. She came to the UK as a Rhodes scholar, left the University of Oxford for a scholarship to Harvard, and ended up with degrees not only in medicine but in history and public policy. Thus equipped she took a job in health policy at University College, London. In the early 1990s Donald played a key role in the Front-Line Evidence Based Medicine Project, an attempt to find out if it was feasible for hospital doctors to apply research evidence in routine clinical practice and to identify key barriers. “She discovered that while doctors weren't opposed to it, there weren't enough electric sockets in the wards. You couldn't plug computers in”, says friend and colleague Trisha Greenhalgh, professor of primary health care at University College, London. 1997 found Donald working on the development of the BMJ Group's Clinical Evidence. Another in the team was Vivek Muthu. The following year they left to set up a business supplying evidence-based medical information and analysis. They called the company, of which Muthu is still chief executive, Bazian (a homophone of Bayesian). To underline the importance of their work Donald felt it should have the status of a discipline: hence “evidology”. She left the company to return to Australia in 2007, when the breast cancer originally diagnosed 4 years earlier put in a forceful reappearance. What was it about evidence based medicine that got Donald so fired up? Muthu points out that, like him, she had been in Oxford at the time Professor David Sackett arrived from Canada to champion evidence based medicine. Paul Glasziou, professor of evidence based medicine at the University of Oxford, says Donald felt that with medical technology putting increasing pressure on medicine's finite budget it was vital to work out what was worth doing and what wasn't. “She was extremely creative”, says Greenhalgh. “She could be quite stubborn. If she was sure of something she would drive it through. She was systematic, a good organiser, a walking mind map.” Glasziou suggests that, from the outside, she could seem quite formidable. “But she was thoughtful about other people, creative, always bubbling over with ideas.” Muthu also uses the word creative. “She could create things from nothing. A million ideas a minute. Bazian, for example. We co-founded it, but she was the inspiration.” Like many patients confronted with a discouraging prognosis Donald tried some unorthodox therapies. But she resisted falling victim to credulity. “The lack of the most elementary information…is woeful”, she blogged. “The murky mess of claims and promises to people with cancer, who are vulnerable and lack any way of knowing what's what, is quite unacceptable.” Soon after receiving her prognosis Donald told Greenhalgh that she hoped she'd be strong enough to record what it feels like to die because there was a gap in the evidence. Greenhalgh believes she succeeded. “I think we've learned a lot from her about what it is to face death.” Donald leaves a husband, Michael." @default.
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- W2073044265 date "2009-03-01" @default.
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- W2073044265 title "Anna Katherine Donald" @default.
- W2073044265 doi "https://doi.org/10.1016/s0140-6736(09)60597-3" @default.
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