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• W2073074051 abstract "Three antiinflammatory saponin components were isolated from the alkaline hydrolysate of a butanol-soluble portion of Kalopanax pictus bark extract through an in vivo activity-guided fractionation procedure. The hydrolysate showed inhibition of adjuvant induced arthritis in rats. After further fractionation, the ethyl acetate fraction exhibited antiarthritic activity, which resulted in the isolation of α-hederin, α-hederin methyl ester, and kalopanaxsaponin I. All compounds showed inhibition of vascular permeability in mice, but only α-hederin methyl ester showed anticarrageenan activity in rats and antiarthritic activity in rats and mice." @default.
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• W2073074051 date "2003-01-01" @default.
• W2073074051 modified "2023-09-23" @default.
• W2073074051 title "Antiinflammatory Activity of .ALPHA.-Hederin Methyl Ester from the Alkaline Hydrolysate of the Butanol Fraction of Kalopanax pictus Bark Extract." @default.
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• W2073074051 doi "https://doi.org/10.1248/bpb.26.429" @default.
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