FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073136670> ?p ?o ?g. }

• W2073136670 endingPage "119" @default.
• W2073136670 startingPage "111" @default.
• W2073136670 abstract "Under conditions of heat shock at 42 degrees C, mRNAs of HSP (heat shock protein) genes are exported out of the nucleus, whereas bulk poly(A)(+) (polyadenylated) mRNA shows a nuclear accumulation in Saccharomyces cerevisiae. Such a selective mRNA export seems an efficacious strategy of yeast cells to adapt rapidly to stress. Although ethanol stress (10%, v/v) as well as heat shock blocks the export of bulk poly(A)(+) mRNA, the differences and/or similarity between heat shock and ethanol stress in the mechanisms of selective mRNA export still remain to be clarified. We found that ethanol stress induced transcriptional activation of a subset of yeast HSP genes; however, intriguingly, most such transcripts remained in the nucleus in a hyperadenylated state and, as a consequence, were not translated into HSPs. Elimination of ethanol resulted in a rapid shortening of the poly(A) tails of HSP mRNAs, loss of their nuclear retention, and the coincidental synthesis of the respective HSPs. Since HSP mRNAs are selectively exported from the nucleus in heat-shocked cells, yeast cells respond differently to ethanol stress and heat shock in the 3'-processing and transport of HSP mRNAs. Furthermore, these results also suggest that hyperadenylation and nuclear retention of mRNAs might be used as a means to control eukaryotic gene expression under stressed conditions." @default.
• W2073136670 created "2016-06-24" @default.
• W2073136670 creator A5007715914 @default.
• W2073136670 creator A5027364082 @default.
• W2073136670 creator A5058720824 @default.
• W2073136670 creator A5062389943 @default.
• W2073136670 date "2008-07-29" @default.
• W2073136670 modified "2023-09-26" @default.
• W2073136670 title "Heat shock and ethanol stress provoke distinctly different responses in 3′-processing and nuclear export of <i>HSP</i> mRNA in <i>Saccharomyces cerevisiae</i>" @default.
• W2073136670 cites W1539988911 @default.
• W2073136670 cites W1964866269 @default.
• W2073136670 cites W1970070225 @default.
• W2073136670 cites W1970424709 @default.
• W2073136670 cites W1975082668 @default.
• W2073136670 cites W1977049988 @default.
• W2073136670 cites W1989136135 @default.
• W2073136670 cites W1989849863 @default.
• W2073136670 cites W1992040206 @default.
• W2073136670 cites W2001932825 @default.
• W2073136670 cites W2015298553 @default.
• W2073136670 cites W2015468911 @default.
• W2073136670 cites W2028061670 @default.
• W2073136670 cites W2030456774 @default.
• W2073136670 cites W2033221220 @default.
• W2073136670 cites W2035028222 @default.
• W2073136670 cites W2037995131 @default.
• W2073136670 cites W2059025826 @default.
• W2073136670 cites W2063678191 @default.
• W2073136670 cites W2082658854 @default.
• W2073136670 cites W2104775769 @default.
• W2073136670 cites W2105599331 @default.
• W2073136670 cites W2108185386 @default.
• W2073136670 cites W2118093507 @default.
• W2073136670 cites W2118929024 @default.
• W2073136670 cites W2124007474 @default.
• W2073136670 cites W2128498313 @default.
• W2073136670 cites W2132316587 @default.
• W2073136670 cites W2132433958 @default.
• W2073136670 cites W2135140872 @default.
• W2073136670 cites W2136446084 @default.
• W2073136670 cites W2156202665 @default.
• W2073136670 cites W2156532971 @default.
• W2073136670 cites W2160516095 @default.
• W2073136670 cites W2161820092 @default.
• W2073136670 cites W2163180503 @default.
• W2073136670 cites W2164702837 @default.
• W2073136670 cites W2165130891 @default.
• W2073136670 cites W2171324601 @default.
• W2073136670 doi "https://doi.org/10.1042/bj20071567" @default.
• W2073136670 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18442359" @default.
• W2073136670 hasPublicationYear "2008" @default.
• W2073136670 type Work @default.
• W2073136670 sameAs 2073136670 @default.
• W2073136670 citedByCount "29" @default.
• W2073136670 countsByYear W20731366702012 @default.
• W2073136670 countsByYear W20731366702014 @default.
• W2073136670 countsByYear W20731366702015 @default.
• W2073136670 countsByYear W20731366702016 @default.
• W2073136670 countsByYear W20731366702018 @default.
• W2073136670 countsByYear W20731366702019 @default.
• W2073136670 countsByYear W20731366702020 @default.
• W2073136670 countsByYear W20731366702021 @default.
• W2073136670 countsByYear W20731366702022 @default.
• W2073136670 crossrefType "journal-article" @default.
• W2073136670 hasAuthorship W2073136670A5007715914 @default.
• W2073136670 hasAuthorship W2073136670A5027364082 @default.
• W2073136670 hasAuthorship W2073136670A5058720824 @default.
• W2073136670 hasAuthorship W2073136670A5062389943 @default.
• W2073136670 hasConcept C104317684 @default.
• W2073136670 hasConcept C105580179 @default.
• W2073136670 hasConcept C150194340 @default.
• W2073136670 hasConcept C153911025 @default.
• W2073136670 hasConcept C185592680 @default.
• W2073136670 hasConcept C205260736 @default.
• W2073136670 hasConcept C2777576037 @default.
• W2073136670 hasConcept C2779222958 @default.
• W2073136670 hasConcept C2780161600 @default.
• W2073136670 hasConcept C2780723820 @default.
• W2073136670 hasConcept C55493867 @default.
• W2073136670 hasConcept C68991219 @default.
• W2073136670 hasConcept C86803240 @default.
• W2073136670 hasConcept C95444343 @default.
• W2073136670 hasConceptScore W2073136670C104317684 @default.
• W2073136670 hasConceptScore W2073136670C105580179 @default.
• W2073136670 hasConceptScore W2073136670C150194340 @default.
• W2073136670 hasConceptScore W2073136670C153911025 @default.
• W2073136670 hasConceptScore W2073136670C185592680 @default.
• W2073136670 hasConceptScore W2073136670C205260736 @default.
• W2073136670 hasConceptScore W2073136670C2777576037 @default.
• W2073136670 hasConceptScore W2073136670C2779222958 @default.
• W2073136670 hasConceptScore W2073136670C2780161600 @default.
• W2073136670 hasConceptScore W2073136670C2780723820 @default.
• W2073136670 hasConceptScore W2073136670C55493867 @default.
• W2073136670 hasConceptScore W2073136670C68991219 @default.
• W2073136670 hasConceptScore W2073136670C86803240 @default.
• W2073136670 hasConceptScore W2073136670C95444343 @default.
• W2073136670 hasIssue "1" @default.
• W2073136670 hasLocation W20731366701 @default.

• next