Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073143902> ?p ?o ?g. }
- W2073143902 endingPage "21" @default.
- W2073143902 startingPage "11" @default.
- W2073143902 abstract "The stubborn chemoresistance of pancreatic ductal adenocarcinoma (PDA) is simultaneously influenced by tumor parenchymal and stromal factors, and the ctritical role of Notch ligand Delta-like 4 (DLL4) in the regulation of tumor malignancies has been observed. DLL4 positive expression ratio between duct cells from clinical tumor and adjacent tissues was statistically significant, and the overactivation of DLL4/Notch pathway enhanced the phenotype of EMT and cancer stem cell, even can induce multi-chemoresistance in vitro. Notably, the accompanied defective angiogenesis directly induced inefficient chemo-drug delivery in vivo. Collectively, overexpressed DLL4 on neoplastic cells can enhance chemoresistance through angiogenesis-dependent/independent mechanisms in PDA." @default.
- W2073143902 created "2016-06-24" @default.
- W2073143902 creator A5008230312 @default.
- W2073143902 creator A5011877804 @default.
- W2073143902 creator A5012987620 @default.
- W2073143902 creator A5015203467 @default.
- W2073143902 creator A5035121335 @default.
- W2073143902 creator A5038482324 @default.
- W2073143902 creator A5047170729 @default.
- W2073143902 creator A5063681878 @default.
- W2073143902 creator A5076721156 @default.
- W2073143902 creator A5083581113 @default.
- W2073143902 date "2013-03-01" @default.
- W2073143902 modified "2023-10-14" @default.
- W2073143902 title "Delta like ligand 4 induces impaired chemo-drug delivery and enhanced chemoresistance in pancreatic cancer" @default.
- W2073143902 cites W1546427377 @default.
- W2073143902 cites W1734170005 @default.
- W2073143902 cites W1970792104 @default.
- W2073143902 cites W1977075884 @default.
- W2073143902 cites W1978139448 @default.
- W2073143902 cites W1978421122 @default.
- W2073143902 cites W1979342940 @default.
- W2073143902 cites W1984428314 @default.
- W2073143902 cites W1987662957 @default.
- W2073143902 cites W1991617381 @default.
- W2073143902 cites W1993223771 @default.
- W2073143902 cites W2000289892 @default.
- W2073143902 cites W2001914873 @default.
- W2073143902 cites W2006723371 @default.
- W2073143902 cites W2007731740 @default.
- W2073143902 cites W2014016903 @default.
- W2073143902 cites W2016093753 @default.
- W2073143902 cites W2021310315 @default.
- W2073143902 cites W2022822197 @default.
- W2073143902 cites W2024898671 @default.
- W2073143902 cites W2025518062 @default.
- W2073143902 cites W2031725458 @default.
- W2073143902 cites W2040224956 @default.
- W2073143902 cites W2040827891 @default.
- W2073143902 cites W2041343513 @default.
- W2073143902 cites W2042015199 @default.
- W2073143902 cites W2045324074 @default.
- W2073143902 cites W2060543662 @default.
- W2073143902 cites W2061876263 @default.
- W2073143902 cites W2062069198 @default.
- W2073143902 cites W2068416436 @default.
- W2073143902 cites W2068675926 @default.
- W2073143902 cites W2069481318 @default.
- W2073143902 cites W2073465941 @default.
- W2073143902 cites W2075773133 @default.
- W2073143902 cites W2076274098 @default.
- W2073143902 cites W2077223423 @default.
- W2073143902 cites W2079142824 @default.
- W2073143902 cites W2080237506 @default.
- W2073143902 cites W2081028905 @default.
- W2073143902 cites W2081777956 @default.
- W2073143902 cites W2091301590 @default.
- W2073143902 cites W2093298375 @default.
- W2073143902 cites W2096939480 @default.
- W2073143902 cites W2100751052 @default.
- W2073143902 cites W2104139707 @default.
- W2073143902 cites W2106787323 @default.
- W2073143902 cites W2107277218 @default.
- W2073143902 cites W2107441200 @default.
- W2073143902 cites W2109579880 @default.
- W2073143902 cites W2115898240 @default.
- W2073143902 cites W2123366765 @default.
- W2073143902 cites W2124396025 @default.
- W2073143902 cites W2128095147 @default.
- W2073143902 cites W2133750440 @default.
- W2073143902 cites W2135339246 @default.
- W2073143902 cites W2137478221 @default.
- W2073143902 cites W2140836243 @default.
- W2073143902 cites W2144893998 @default.
- W2073143902 cites W2147892446 @default.
- W2073143902 cites W2160947862 @default.
- W2073143902 cites W2161532329 @default.
- W2073143902 cites W2170785598 @default.
- W2073143902 cites W4247785462 @default.
- W2073143902 doi "https://doi.org/10.1016/j.canlet.2012.11.015" @default.
- W2073143902 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23200678" @default.
- W2073143902 hasPublicationYear "2013" @default.
- W2073143902 type Work @default.
- W2073143902 sameAs 2073143902 @default.
- W2073143902 citedByCount "41" @default.
- W2073143902 countsByYear W20731439022013 @default.
- W2073143902 countsByYear W20731439022014 @default.
- W2073143902 countsByYear W20731439022015 @default.
- W2073143902 countsByYear W20731439022016 @default.
- W2073143902 countsByYear W20731439022017 @default.
- W2073143902 countsByYear W20731439022018 @default.
- W2073143902 countsByYear W20731439022019 @default.
- W2073143902 countsByYear W20731439022020 @default.
- W2073143902 countsByYear W20731439022021 @default.
- W2073143902 countsByYear W20731439022022 @default.
- W2073143902 countsByYear W20731439022023 @default.
- W2073143902 crossrefType "journal-article" @default.
- W2073143902 hasAuthorship W2073143902A5008230312 @default.