FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073158462> ?p ?o ?g. }

• W2073158462 endingPage "22025" @default.
• W2073158462 startingPage "22020" @default.
• W2073158462 abstract "Isochorismate synthase (ICS) converts chorismate to isochorismate for the biosynthesis of phylloquinone, an essential cofactor for photosynthetic electron transport. ICS is also required for salicylic acid (SA) synthesis during Arabidopsis defense. In several other species, including Populus, SA is derived primarily from the phenylpropanoid pathway. We therefore sought to investigate ICS regulation in Populus to learn the extent of ICS involvement in SA synthesis and defense. Arabidopsis harbors duplicated AtICS genes that differ in their exon-intron structure, basal expression, and stress inducibility. In contrast, we found a single ICS gene in Populus and six other sequenced plant genomes, pointing to the AtICS duplication as a lineage-specific event. The Populus ICS encodes a functional plastidic enzyme, and was not responsive to stresses that stimulated phenylpropanoid accumulation. Populus ICS underwent extensive alternative splicing that was rare for the duplicated AtICSs. Sequencing of 184 RT-PCR Populus clones revealed 37 alternative splice variants, with normal transcripts representing approximately 50% of the population. When expressed in Arabidopsis, Populus ICS again underwent alternative splicing, but did not produce normal transcripts to complement AtICS1 function. The splice-site sequences of Populus ICS are unusual, suggesting a causal link between junction sequence, alternative splicing, and ICS function. We propose that gene duplication and alternative splicing of ICS evolved independently in Arabidopsis and Populus in accordance with their distinct defense strategies. AtICS1 represents a divergent isoform for inducible SA synthesis during defense. Populus ICS primarily functions in phylloquinone biosynthesis, a process that can be sustained at low ICS transcript levels." @default.
• W2073158462 created "2016-06-24" @default.
• W2073158462 creator A5000765323 @default.
• W2073158462 creator A5003719587 @default.
• W2073158462 creator A5020299359 @default.
• W2073158462 creator A5020724933 @default.
• W2073158462 creator A5028554303 @default.
• W2073158462 creator A5042751225 @default.
• W2073158462 creator A5046975725 @default.
• W2073158462 creator A5083442860 @default.
• W2073158462 date "2009-12-22" @default.
• W2073158462 modified "2023-09-25" @default.
• W2073158462 title "Alternative splicing and gene duplication differentially shaped the regulation of isochorismate synthase in <i>Populus</i> and <i>Arabidopsis</i>" @default.
• W2073158462 cites W1095894567 @default.
• W2073158462 cites W1967205151 @default.
• W2073158462 cites W1974071568 @default.
• W2073158462 cites W1976466023 @default.
• W2073158462 cites W1994145712 @default.
• W2073158462 cites W1995444885 @default.
• W2073158462 cites W19976897 @default.
• W2073158462 cites W2002756441 @default.
• W2073158462 cites W2010219916 @default.
• W2073158462 cites W2013740990 @default.
• W2073158462 cites W2017162186 @default.
• W2073158462 cites W2022685385 @default.
• W2073158462 cites W2024646179 @default.
• W2073158462 cites W2038335468 @default.
• W2073158462 cites W2040770546 @default.
• W2073158462 cites W2041519537 @default.
• W2073158462 cites W2067135771 @default.
• W2073158462 cites W2068171908 @default.
• W2073158462 cites W2072910291 @default.
• W2073158462 cites W2075347516 @default.
• W2073158462 cites W2089242611 @default.
• W2073158462 cites W2099773364 @default.
• W2073158462 cites W2100202678 @default.
• W2073158462 cites W2101466802 @default.
• W2073158462 cites W2105927944 @default.
• W2073158462 cites W2110899053 @default.
• W2073158462 cites W2113286177 @default.
• W2073158462 cites W2118512972 @default.
• W2073158462 cites W2125346198 @default.
• W2073158462 cites W2136462728 @default.
• W2073158462 cites W2143345980 @default.
• W2073158462 cites W2144868934 @default.
• W2073158462 cites W2145070407 @default.
• W2073158462 cites W2149517531 @default.
• W2073158462 cites W2150245940 @default.
• W2073158462 cites W2152458080 @default.
• W2073158462 cites W2153488363 @default.
• W2073158462 cites W2153579981 @default.
• W2073158462 cites W2156622081 @default.
• W2073158462 cites W2158726059 @default.
• W2073158462 cites W2159356563 @default.
• W2073158462 cites W2164329780 @default.
• W2073158462 cites W2164472615 @default.
• W2073158462 cites W2165535624 @default.
• W2073158462 cites W2171520124 @default.
• W2073158462 cites W2303011501 @default.
• W2073158462 cites W2950851297 @default.
• W2073158462 doi "https://doi.org/10.1073/pnas.0906869106" @default.
• W2073158462 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2790362" @default.
• W2073158462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19996170" @default.
• W2073158462 hasPublicationYear "2009" @default.
• W2073158462 type Work @default.
• W2073158462 sameAs 2073158462 @default.
• W2073158462 citedByCount "70" @default.
• W2073158462 countsByYear W20731584622012 @default.
• W2073158462 countsByYear W20731584622013 @default.
• W2073158462 countsByYear W20731584622014 @default.
• W2073158462 countsByYear W20731584622015 @default.
• W2073158462 countsByYear W20731584622016 @default.
• W2073158462 countsByYear W20731584622017 @default.
• W2073158462 countsByYear W20731584622018 @default.
• W2073158462 countsByYear W20731584622019 @default.
• W2073158462 countsByYear W20731584622020 @default.
• W2073158462 countsByYear W20731584622021 @default.
• W2073158462 countsByYear W20731584622022 @default.
• W2073158462 countsByYear W20731584622023 @default.
• W2073158462 crossrefType "journal-article" @default.
• W2073158462 hasAuthorship W2073158462A5000765323 @default.
• W2073158462 hasAuthorship W2073158462A5003719587 @default.
• W2073158462 hasAuthorship W2073158462A5020299359 @default.
• W2073158462 hasAuthorship W2073158462A5020724933 @default.
• W2073158462 hasAuthorship W2073158462A5028554303 @default.
• W2073158462 hasAuthorship W2073158462A5042751225 @default.
• W2073158462 hasAuthorship W2073158462A5046975725 @default.
• W2073158462 hasAuthorship W2073158462A5083442860 @default.
• W2073158462 hasBestOaLocation W20731584622 @default.
• W2073158462 hasConcept C103077935 @default.
• W2073158462 hasConcept C104317684 @default.
• W2073158462 hasConcept C141231307 @default.
• W2073158462 hasConcept C143065580 @default.
• W2073158462 hasConcept C194583182 @default.
• W2073158462 hasConcept C2776559899 @default.
• W2073158462 hasConcept C2779491563 @default.
• W2073158462 hasConcept C36823959 @default.
• W2073158462 hasConcept C54355233 @default.

• next