Matches in SemOpenAlex for { <https://semopenalex.org/work/W2073161926> ?p ?o ?g. }
- W2073161926 abstract "Most strokes are covert and observed incidentally on brain scans, but their presence increases risk of overt stroke and dementia. Amyloid angiopathy, associated with Alzheimer Disease (AD) causes stroke, and when even small strokes coexist with AD, they lower the threshold for dementia. Diffuse ischemic white matter disease impairs executive functioning, information processing speed, and gait. Neuroimaging techniques, such as tissue segmentation, Diffusion Tensor Imaging, MR Spectroscopy, functional MRI and amyloid PET, probe microstructural integrity, molecular biology, and activation patterns, providing new insights into brain-behavior relationships. MR-pathological studies of periventricular hyperintensity (leukoaraiosis) in aging and dementia reveal arteriolar tortuosity, reduced vessel density, and occlusive venous collagenosis which causes venous insufficiency and vasogenic edema. Activated microglia, oligodendroglial apoptosis, clasmatodendritic astrocytosis, and upregulated hypoxia-markers are seen on immunohistochemistry. Further research is needed to understand and treat this chronic subcortical vascular disease, which is epidemic in our aging population." @default.
- W2073161926 created "2016-06-24" @default.
- W2073161926 creator A5050914325 @default.
- W2073161926 creator A5053189174 @default.
- W2073161926 creator A5074842638 @default.
- W2073161926 date "2009-03-01" @default.
- W2073161926 modified "2023-10-15" @default.
- W2073161926 title "Understanding White Matter Disease" @default.
- W2073161926 cites W1217365060 @default.
- W2073161926 cites W1606825164 @default.
- W2073161926 cites W1839080396 @default.
- W2073161926 cites W1859451507 @default.
- W2073161926 cites W1870043354 @default.
- W2073161926 cites W1975552740 @default.
- W2073161926 cites W1976007116 @default.
- W2073161926 cites W1979243823 @default.
- W2073161926 cites W1984061911 @default.
- W2073161926 cites W1986159654 @default.
- W2073161926 cites W1987927388 @default.
- W2073161926 cites W1996304178 @default.
- W2073161926 cites W1996470432 @default.
- W2073161926 cites W2007777166 @default.
- W2073161926 cites W2009036027 @default.
- W2073161926 cites W2009739635 @default.
- W2073161926 cites W2012133068 @default.
- W2073161926 cites W2016349161 @default.
- W2073161926 cites W2019251961 @default.
- W2073161926 cites W2023649381 @default.
- W2073161926 cites W2043592305 @default.
- W2073161926 cites W2043670258 @default.
- W2073161926 cites W2046429594 @default.
- W2073161926 cites W2048943469 @default.
- W2073161926 cites W2050784521 @default.
- W2073161926 cites W2055127113 @default.
- W2073161926 cites W2064176622 @default.
- W2073161926 cites W2070646430 @default.
- W2073161926 cites W2072602970 @default.
- W2073161926 cites W2077066095 @default.
- W2073161926 cites W2077583762 @default.
- W2073161926 cites W2084948736 @default.
- W2073161926 cites W2090016962 @default.
- W2073161926 cites W2093144777 @default.
- W2073161926 cites W2104591424 @default.
- W2073161926 cites W2104855192 @default.
- W2073161926 cites W2106961136 @default.
- W2073161926 cites W2109598200 @default.
- W2073161926 cites W2113727732 @default.
- W2073161926 cites W2119266884 @default.
- W2073161926 cites W2132851971 @default.
- W2073161926 cites W2135070546 @default.
- W2073161926 cites W2136239752 @default.
- W2073161926 cites W2137011929 @default.
- W2073161926 cites W2152223730 @default.
- W2073161926 cites W2163718643 @default.
- W2073161926 cites W2164273040 @default.
- W2073161926 cites W2165773859 @default.
- W2073161926 cites W2170621670 @default.
- W2073161926 cites W2170656454 @default.
- W2073161926 cites W2223656268 @default.
- W2073161926 cites W4240347348 @default.
- W2073161926 cites W4296588155 @default.
- W2073161926 doi "https://doi.org/10.1161/strokeaha.108.537704" @default.
- W2073161926 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19064767" @default.
- W2073161926 hasPublicationYear "2009" @default.
- W2073161926 type Work @default.
- W2073161926 sameAs 2073161926 @default.
- W2073161926 citedByCount "313" @default.
- W2073161926 countsByYear W20731619262012 @default.
- W2073161926 countsByYear W20731619262013 @default.
- W2073161926 countsByYear W20731619262014 @default.
- W2073161926 countsByYear W20731619262015 @default.
- W2073161926 countsByYear W20731619262016 @default.
- W2073161926 countsByYear W20731619262017 @default.
- W2073161926 countsByYear W20731619262018 @default.
- W2073161926 countsByYear W20731619262019 @default.
- W2073161926 countsByYear W20731619262020 @default.
- W2073161926 countsByYear W20731619262021 @default.
- W2073161926 countsByYear W20731619262022 @default.
- W2073161926 countsByYear W20731619262023 @default.
- W2073161926 crossrefType "journal-article" @default.
- W2073161926 hasAuthorship W2073161926A5050914325 @default.
- W2073161926 hasAuthorship W2073161926A5053189174 @default.
- W2073161926 hasAuthorship W2073161926A5074842638 @default.
- W2073161926 hasBestOaLocation W20731619261 @default.
- W2073161926 hasConcept C118552586 @default.
- W2073161926 hasConcept C126838900 @default.
- W2073161926 hasConcept C127413603 @default.
- W2073161926 hasConcept C142724271 @default.
- W2073161926 hasConcept C143409427 @default.
- W2073161926 hasConcept C146638467 @default.
- W2073161926 hasConcept C149550507 @default.
- W2073161926 hasConcept C15744967 @default.
- W2073161926 hasConcept C169760540 @default.
- W2073161926 hasConcept C204232928 @default.
- W2073161926 hasConcept C2776191500 @default.
- W2073161926 hasConcept C2777790613 @default.
- W2073161926 hasConcept C2777952318 @default.
- W2073161926 hasConcept C2779134260 @default.
- W2073161926 hasConcept C2779483572 @default.
- W2073161926 hasConcept C2780645631 @default.